Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.35 |
| ▸ | DRD1 | P21728 | 4/20 | 0.34 |
| ▸ | MET | P08581 | 3/20 | 0.31 |
| ▸ | HIPK4 | Q8NE63 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30840025 | 1.00 | TRPA1 (0.35) | TRPA1DRD1METHIPK4 | |
| Iodide SCHEMBL30841178 | 0.99 | TRPA1 (0.34) | TRPA1DRD1METHIPK4 | |
| SCHEMBL30750357 | 0.86 | TRPA1 (0.34) | TRPA1DRD1MET | |
| Iodide SCHEMBL31671174 | 0.85 | TRPA1 (0.33) | TRPA1DRD1MET | |
| SCHEMBL27286857 | 0.85 | — | — | |
| SCHEMBL30841237 | 0.85 | — | — | |
| SCHEMBL30840300 | 0.84 | HIPK4 (0.30) | HIPK4 | |
| SCHEMBL27286789 | 0.84 | HIPK4 (0.30) | HIPK4 | |
| SCHEMBL31625861 | 0.82 | MET (0.38) | TRPA1DRD1MET | |
| SCHEMBL27275542 | 0.82 | MET (0.38) | TRPA1DRD1MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024054840-A1 | MACROCYCLIC COMPOUNDS, COMPOSITIONS, AND METHODS OF USING THEREOF | SIONNA THERAPEUTICS (US) | 2024-03-14 | — | — | WO | disclosed |