Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.54 |
| ▸ | RAB9A | P51151 | 5/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | LDHA | P00338 | 1/20 | 0.46 |
| ▸ | ALPL | P05186 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CASP3 | P42574 | 2/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | AXL | P30530 | 2/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30930704 | 1.00 | NPC1 (0.54) | NPC1RAB9ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL27285125 | 0.83 | NPC1 (0.49) | NPC1RAB9ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL30930671 | 0.82 | AXL (0.53) | LDHASMN1; SMN2MAPTDHODHAXL | |
| SCHEMBL30930680 | 0.80 | AXL (0.58) | NPC1RAB9ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL27284549 | 0.80 | AXL (0.58) | NPC1RAB9ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL30930605 | 0.79 | KDM4E (0.53) | NPC1RAB9ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL27285080 | 0.79 | KDM4E (0.53) | NPC1RAB9ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL20556399 | 0.77 | L3MBTL1 (0.40) | NPC1RAB9ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL29492904 | 0.77 | L3MBTL1 (0.40) | NPC1RAB9ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL31636734 | 0.76 | LDHA (0.72) | NPC1RAB9ALDHASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024096753-A1 | NEK7 DEGRADERS AND METHODS OF USE THEREOF | CAPTOR THERAPEUTICS S.A. (PL) | 2024-05-10 | — | — | WO | disclosed |
| WO-2024094819-A1 | NEK7 DEGRADERS AND METHODS OF USE THEREOF | CAPTOR THERAPEUTICS S.A. (PL) | 2024-05-10 | — | — | WO | disclosed |
| WO-2024094819-A1 | NEK7 DEGRADERS AND METHODS OF USE THEREOF | CAPTOR THERAPEUTICS S.A. (PL) | 2024-05-10 | — | — | WO | disclosed |