Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2401515 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL819027 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL7935941 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL7936053 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL7935489 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL7623369 | 0.69 | — | — | |
| Hydrochloric Acid SCHEMBL7623375 | 0.69 | — | — | |
| SCHEMBL7635776 | 0.67 | ALDH1A1 (0.35) | — | |
| SCHEMBL1824459 | 0.67 | ALDH1A1 (0.35) | — | |
| Hydrochloric Acid SCHEMBL27521222 | 0.66 | SIGMAR1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1824888-B1 | MONOCYCLOPENTADIENYL COMPLEXES | BASELL POLYOLEFINE GMBH (DE) | 2017-01-18 | — | — | EP | disclosed |
| EP-1740626-B1 | CATALYST SYSTEM FOR OLEFIN POLYMERIZATION, ITS PRODUCTION AND USE | BASELL POLYOLEFINE GMBH (DE) | 2014-10-22 | — | — | EP | disclosed |
| EP-2173778-B1 | CATALYST SYSTEM FOR POLYMERIZATION OF OLEFINIC MONOMERS, PROCESS FOR PREPARING POLYMERS AND POLYMERS PREPARED BY THE PROCESS | BASELL POLYOLEFINE GMBH (DE) | 2012-04-18 | — | — | EP | disclosed |
| US-8133832-B2 | Catalyst system for polymerization of olefinic monomers, process for preparing polymers, and polymers prepared by the process | BASELL POLYOLEFINE GMBH (DE) | 2012-03-13 | — | — | US | disclosed |
| EP-1861409-B1 | MONOCYCLOPENTADIENYL COMPLEXES | BASELL POLYOLEFINE GMBH (DE) | 2011-01-19 | — | — | EP | disclosed |
| US-7795167-B2 | Cyclopentadienyl complexes of group 6 substituted by silyl halides | BASELL POLYOLEFINE GMBH (DE) | 2010-09-14 | — | — | US | disclosed |
| US-7776980-B2 | Monocyclopentadienyl complexes | BASELL POLYOLEFINE GMBH (DE) | 2010-08-17 | — | — | US | disclosed |
| US-20100190931-A1 | CATALYST SYSTEM FOR POLYMERIZATION OF OLEFINIC MONOMERS, PROCESS FOR PREPARING POLYMERS, AND POLYMERS PREPARED BY THE PROCESS | BASELL POLYOLEFINE GMBH (DE) | 2010-07-29 | — | — | US | disclosed |
| EP-2173778-A1 | CATALYST SYSTEM FOR POLYMERIZATION OF OLEFINIC MONOMERS, PROCESS FOR PREPARING POLYMERS AND POLYMERS PREPARED BY THE PROCESS | Basell Polyolefine GmbH (DE) | 2010-04-14 | — | — | EP | disclosed |
| US-7671148-B2 | Mixing organic transition metal compounds, hydrolyzed organoaluminum compound, and solvent, then impregnating dry porous support | BASELL POLYOLEFINE GMBH (DE) | 2010-03-02 | — | — | US | disclosed |
| EP-1694689-A1 | MONOCYCLOPENTADIENYL COMPLEXES | Basell Polyolefine GmbH (DE) | 2006-08-30 | — | — | EP | disclosed |
| WO-2006063826-A1 | MONOCYCLOPENTADIENYL COMPLEXES | BASELL POLYOLEFINE GMBH (DE) | 2006-06-22 | — | — | WO | disclosed |
| WO-2006018264-A2 | CYCLOPENTADIENYL COMPLEXES OF GROUP 6 SUBSTITUTED BY SILYL HALIDES | BASELL POLYOLEFINE GMBH (DE) | 2006-02-23 | — | — | WO | disclosed |
| WO-2005103099-A1 | CATALYST SYSTEM FOR OLEFIN POLYMERIZATION, ITS PRODUCTION AND USE | BASELL POLYOLEFINE GMBH (DE) | 2005-11-03 | — | — | WO | disclosed |
| WO-2005058983-A2 | MONOCYCLOPENTADIENYL COMPLEXES | BASELL POLYOLEFINE GMBH (DE) | 2005-06-30 | — | — | WO | disclosed |
| WO-2005058928-A1 | MONOCYCLOPENTADIENYL COMPLEXES | BASELL POLYOLEFINE GMBH (DE) | 2005-06-30 | — | — | WO | disclosed |
| US-20020077432-A1 | Copolymerization of olefins | BENNETT ALISON MARGARET ANNE (US) | 2002-06-20 | — | — | US | disclosed |
| US-6384144-B1 | TWO DIFFERENT POLYMERIZATION CATALYSTS OF WHICH A) AT LEAST ONE IS A POLYMERIZATION CATALYST BASED ON AN EARLY TRANSITION METAL COMPONENT AND B) AT LEAST ONE IS A POLYMERIZATION CATALYST BASED ON A LATE TRANSITION METAL COMPONENT. | BASELL POLYPROPYLEN GMBH (DE) | 2002-05-07 | — | — | US | disclosed |
| US-20020026012-A1 | CATALYST COMPOSITION | EQUISTAR CHEMICALS, LP | 2002-02-28 | — | — | US | disclosed |
| US-6262196-B1 | AS POLYMERIZATION CATALYST IN POLYMERIZATION OF OLEFINS | TARGOR GMBH (DE) | 2001-07-17 | — | — | US | disclosed |