SCHEMBL27286014

SCHEMBL27286014

CCCCc1cc(C(C)C)ccc1C(C)C

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 2/20 0.38
RORA P35398 1/20 0.35
RORC P51449 1/20 0.35
RORB Q92753 1/20 0.35
UCHL3 P15374 2/20 0.35
LMNA P02545 1/20 0.34
HTR1D P28221 2/20 0.34
TRPA1 O75762 1/20 0.33
PTGS1 P23219 1/20 0.33
CACNA1C Q13936 1/20 0.33
CASR P41180 1/20 0.33
NPC1 O15118 1/20 0.33
HPGD P15428 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
CNR1 P21554 1/20 0.33
CNR2 P34972 1/20 0.33
EPHX1 P07099 1/20 0.33
HTR1B P28222 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17318269 0.93 TYR (0.41) TYRLMNAPTGS1CNR1CNR2
SCHEMBL27252554 0.89 PPARG (0.38) LMNAHTR1DTRPA1PTGS1CACNA1C
SCHEMBL5381021 0.80 TYR (0.58) TYRLMNAPTGS1HTTMEN1
SCHEMBL22341564 0.80 CRHR1 (0.37) TYRRORARORCRORBUCHL3
SCHEMBL5166613 0.80 TYR (0.49) TYRLMNATRPA1PTGS1CACNA1C
SCHEMBL18951094 0.80 CYP1A2 (0.37) TYRLMNATRPA1NPC1HPGD
SCHEMBL28984991 0.79 HTR2A (0.39) TYRRORARORCRORBUCHL3
SCHEMBL8638358 0.78 LMNA (0.40) TYRLMNAHTR1DTRPA1PTGS1
SCHEMBL11575821 0.76 LMNA (0.46) TYRLMNATRPA1PTGS1CACNA1C
SCHEMBL5164478 0.76 TYR (0.62) TYRTRPA1PTGS1CACNA1CNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1013089-B Process for producing double-layer foam molded article MITSUI PETROCHEMICAL IND (JP) 1991-07-10 CN disclosed
CN-1031345-A The method for making of two-ply foam molded articles MITSUI PETROCHEMICAL IND (JP) 1989-03-01 CN disclosed