Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CASR | P41180 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27296313 | 0.86 | MAPT (0.46) | ALDH1A1MAPTTSHRMEN1KMT2A | |
| SCHEMBL28623470 | 0.84 | ALDH1A1 (0.49) | ALDH1A1MAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL13808926 | 0.79 | ALDH1A1 (0.70) | ALDH1A1MAPTTSHRMEN1KMT2A | |
| SCHEMBL14624383 | 0.79 | AKR1C3 (0.50) | ALDH1A1MAPTTSHRMEN1KMT2A | |
| SCHEMBL27347830 | 0.79 | HDAC1 (0.44) | ALDH1A1MAPTTSHRMEN1KMT2A | |
| SCHEMBL6622364 | 0.78 | ALDH1A1 (1.00) | ALDH1A1MAPTTSHRMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL6624955 | 0.76 | ALDH1A1 (0.96) | ALDH1A1MAPTTSHRMEN1KMT2A | |
| SCHEMBL24003733 | 0.75 | RAB9A (0.46) | ALDH1A1MAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL3335783 | 0.75 | ALDH1A1 (0.69) | ALDH1A1MAPTTSHRMEN1KMT2A | |
| SCHEMBL1459456 | 0.75 | ALDH1A1 (0.71) | ALDH1A1MAPTTSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100422146-C | Synthesis method of indapamide | TIANJIN LISHENG PHARMACEUTICAL (CN) | 2008-10-01 | — | — | CN | claimed |
| CN-1927833-A | Synthesis method of indapamide | TIANJIN LISHENG PHARMACEUTICAL (CN) | 2007-03-14 | — | — | CN | claimed |
| CN-119751330-A | Synthesis method of indapamide intermediate-N-amino-2-methylindoline hydrochloride | 天津力生制药股份有限公司 | 2025-04-04 | — | — | CN | disclosed |
| CN-116041228-B | Synthesis method of bumetanide | 沈阳希贝康医药科技有限公司 | 2024-03-12 | — | — | CN | disclosed |
| CN-116219512-A | PPA electroplated tail pipe part and production process thereof | 宁波四维尔工业有限责任公司 | 2023-06-06 | — | — | CN | disclosed |
| CN-116041228-A | Synthesis method of bumetanide | 沈阳希贝康医药科技有限公司 | 2023-05-02 | — | — | CN | disclosed |
| CN-115724641-A | Mildew-proof antibacterial autoclaved aerated building block and preparation method thereof | 广州市贤达建材有限公司 | 2023-03-03 | — | — | CN | disclosed |
| CN-108997176-B | 4-chloro-N-substituted phenyl-3-sulfonyl aminobenzamide compound, and preparation and anti-tumor application thereof | 温州医科大学 | 2021-07-02 | — | — | CN | disclosed |
| CN-110538160-A | indapamide tablet and preparation method thereof | SUICHENG PHARMACEUTICAL CO LTD | 2019-12-06 | — | — | CN | disclosed |
| CN-100422146-C | Synthesis method of indapamide | TIANJIN LISHENG PHARMACEUTICAL (CN) | 2008-10-01 | — | — | CN | disclosed |
| CN-100422146-C | Synthesis method of indapamide | TIANJIN LISHENG PHARMACEUTICAL (CN) | 2008-10-01 | — | — | CN | disclosed |
| CN-1927833-A | Synthesis method of indapamide | TIANJIN LISHENG PHARMACEUTICAL (CN) | 2007-03-14 | — | — | CN | disclosed |
| CN-1927833-A | Synthesis method of indapamide | TIANJIN LISHENG PHARMACEUTICAL (CN) | 2007-03-14 | — | — | CN | disclosed |
| CN-1639141-A | Novel thiadiazoles and oxadiazoles and their use as phosphodiesterase-7 inhibitors | WARNER LAMBERT CO (US) | 2005-07-13 | — | — | CN | disclosed |
| CN-1012642-B | Process for preparing sulfamoylbenzoic acid derivatives | KYORIN SEIYAKU KK (JP) | 1991-05-22 | — | — | CN | disclosed |
| CN-85108940-A | The preparation method of sulfamoylbenzoic acid derivatives | — | 1986-10-22 | — | — | CN | disclosed |