Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CASR | P41180 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27286217 | 0.86 | ALDH1A1 (0.64) | MAPTALDH1A1HDAC1HDAC8HDAC6 | |
| SCHEMBL28623470 | 0.84 | ALDH1A1 (0.49) | MAPTALDH1A1HDAC1HDAC8HDAC6 | |
| SCHEMBL29056188 | 0.75 | MEN1 (0.50) | MAPTALDH1A1HDAC1HDAC6MEN1 | |
| SCHEMBL11281570 | 0.74 | ALDH1A1 (0.45) | MAPTALDH1A1HDAC1HDAC8HDAC6 | |
| SCHEMBL9320197 | 0.72 | ALDH1A1 (0.57) | MAPTALDH1A1HDAC1HDAC8HDAC6 | |
| SCHEMBL110094 | 0.72 | TSHR (0.67) | MAPTTSHRMEN1KMT2APOLB | |
| SCHEMBL29514652 | 0.72 | TSHR (0.67) | MAPTTSHRMEN1KMT2APOLB | |
| SCHEMBL27554865 | 0.72 | MEN1 (0.32) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL28917376 | 0.72 | NPC1 (0.60) | MAPTALDH1A1HDAC8HDAC6MEN1 | |
| SCHEMBL27585059 | 0.71 | ALDH1A1 (0.41) | MAPTALDH1A1MEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108997176-B | 4-chloro-N-substituted phenyl-3-sulfonyl aminobenzamide compound, and preparation and anti-tumor application thereof | 温州医科大学 | 2021-07-02 | — | — | CN | claimed |
| CN-108863860-B | N-substituted phenyl-3-sulfonyl aminobenzamide compound, preparation thereof and application thereof in resisting breast cancer activity | 温州医科大学 | 2021-08-06 | — | — | CN | disclosed |
| CN-108997176-B | 4-chloro-N-substituted phenyl-3-sulfonyl aminobenzamide compound, and preparation and anti-tumor application thereof | 温州医科大学 | 2021-07-02 | — | — | CN | disclosed |
| CN-105418479-A | Indapamide synthetic method | TIANJIN HENGBIDA CHEMICAL COMPOSITION CO LTD | 2016-03-23 | — | — | CN | disclosed |
| CN-100422146-C | Synthesis method of indapamide | TIANJIN LISHENG PHARMACEUTICAL (CN) | 2008-10-01 | — | — | CN | disclosed |
| CN-1927833-A | Synthesis method of indapamide | TIANJIN LISHENG PHARMACEUTICAL (CN) | 2007-03-14 | — | — | CN | disclosed |
| CN-1035502-A | Derivative and preparation method thereof, and the pharmaceutical preparation 2-amino-tetrahydrochysene-different quinoline woods that contains this derivative | CHINOIN GYOGYSZER ES VEGYESZET (HU) | 1989-09-13 | — | — | CN | disclosed |
| CN-85108940-A | The preparation method of sulfamoylbenzoic acid derivatives | — | 1986-10-22 | — | — | CN | disclosed |