SCHEMBL4867801

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL25920561	0.89	NAMPT (0.59)	NAMPTFFAR1FFAR4CA1CA2
	SCHEMBL572740	0.88	IDO1 (0.60)	NAMPTCA1CA2IDO1CTSK
	SCHEMBL752391	0.85	CA1 (0.54)	NAMPTCA1CA2IDO1CA12
	SCHEMBL23291264	0.84	NAMPT (0.57)	NAMPTCA1CA2IDO1CTSK
	SCHEMBL2212224	0.84	RAB9A (0.60)	NAMPTNPC1RAB9AMAPT
	SCHEMBL15599542	0.83	NAMPT (0.56)	NAMPTCA1CA2IDO1CTSK
	Propionic Acid SCHEMBL8529443	0.82	CTSK (0.57)	NAMPTCA1CA2IDO1CTSK
	SCHEMBL18800977	0.82	NAMPT (0.58)	NAMPTCA1CA2IDO1CTSK
	SCHEMBL4863250	0.82	ADRB2 (0.60)	NAMPTCA1CA2CTSKGAA
	SCHEMBL4867710	0.82	ADRB2 (0.60)	NAMPTCA1CA2CTSKGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.