Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.44 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.44 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.44 |
| ▸ | LPAR4 | Q99677 | 1/20 | 0.44 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.44 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.44 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.44 |
| ▸ | PRKCA | P17252 | 3/20 | 0.44 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.44 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.44 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.44 |
| ▸ | DGKA | P23743 | 2/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4282445 | 1.00 | LMNA (0.50) | LMNAMAPTMEN1KMT2AKDM4E | |
| SCHEMBL10275408 | 0.92 | DGKA (0.56) | MAPTENPP2LPAR6LPAR1LPAR4 | |
| SCHEMBL8087624 | 0.79 | MAPK1 (0.49) | LMNAMAPTMEN1KMT2AKDM4E | |
| Glycerin SCHEMBL2718540 | 0.76 | KDM4E (0.59) | LMNAMAPTMEN1KMT2AKDM4E | |
| SCHEMBL2782421 | 0.76 | MAPT (0.46) | LMNAMAPTMEN1KMT2AKDM4E | |
| SCHEMBL25870 | 0.76 | MAPT (0.46) | LMNAMAPTMEN1KMT2AKDM4E | |
| SCHEMBL2783097 | 0.76 | MAPT (0.46) | LMNAMAPTMEN1KMT2AKDM4E | |
| SCHEMBL19019979 | 0.76 | MEN1 (0.43) | LMNAMAPTMEN1KMT2AKDM4E | |
| SCHEMBL669205 | 0.74 | DGKA (0.57) | LMNAMAPTMEN1KMT2AMAPK1 | |
| SCHEMBL11026247 | 0.74 | DGKA (0.57) | LMNAMAPTMEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180311166-A1 | TERNARY MIXTURE FORMULATIONS | WESTERN UNIVERSITY OF HEALTH SCIENCES (US) | 2018-11-01 | — | — | US | claimed |
| US-9808426-B2 | Ternary mixture formulations | WESTERN UNIVERSITY OF HEALTH SCIENCES (US) | 2017-11-07 | — | — | US | claimed |
| US-20170128368-A1 | TERNARY MIXTURE FORMULATIONS | WESTERN UNIVERSITY OF HEALTH SCIENCES (US) | 2017-05-11 | — | — | US | claimed |
| US-9492387-B2 | Ternary mixture formulations | WESTERN UNIVERSITY OF HEALTH SCIENCES (US) | 2016-11-15 | — | — | US | claimed |
| US-20130310397-A1 | TERNARY MIXTURE FORMULATIONS | WESTERN UNIVERSITY OF HEALTH SCIENCES (US) | 2013-11-21 | — | — | US | claimed |
| EP-2632437-A2 | TERNARY MIXTURE FORMULATIONS | Western University Of Health Sciences (US) | 2013-09-04 | — | — | EP | claimed |
| WO-2012058668-A2 | TERNARY MIXTURE FORMULATIONS | WESTERN UNIVERSITY OF HEALTH SCIENCES (US) | 2012-05-03 | — | — | WO | claimed |
| US-20180311166-A1 | TERNARY MIXTURE FORMULATIONS | WESTERN UNIVERSITY OF HEALTH SCIENCES (US) | 2018-11-01 | — | — | US | disclosed |
| US-9808426-B2 | Ternary mixture formulations | WESTERN UNIVERSITY OF HEALTH SCIENCES (US) | 2017-11-07 | — | — | US | disclosed |
| US-20170128368-A1 | TERNARY MIXTURE FORMULATIONS | WESTERN UNIVERSITY OF HEALTH SCIENCES (US) | 2017-05-11 | — | — | US | disclosed |
| US-9492387-B2 | Ternary mixture formulations | WESTERN UNIVERSITY OF HEALTH SCIENCES (US) | 2016-11-15 | — | — | US | disclosed |
| US-20130310397-A1 | TERNARY MIXTURE FORMULATIONS | WESTERN UNIVERSITY OF HEALTH SCIENCES (US) | 2013-11-21 | — | — | US | disclosed |
| EP-2632437-A2 | TERNARY MIXTURE FORMULATIONS | Western University Of Health Sciences (US) | 2013-09-04 | — | — | EP | disclosed |
| WO-2012058668-A2 | TERNARY MIXTURE FORMULATIONS | WESTERN UNIVERSITY OF HEALTH SCIENCES (US) | 2012-05-03 | — | — | WO | disclosed |
| US-20040143093-A1 | In vitro activation of configuration changes in recombinant proteins resulting in increased content of beta -sheet secondary structure (amyloidogenic aggregates) for use in modelin and treating nervous system, brain and autoimmune diseases | EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZURICH (CH) | 2004-07-22 | — | — | US | disclosed |
| EP-1414854-A1 | METHOD FOR INDUCING A CONFORMATIONAL TRANSITION IN PROTEINS SUCH AS PATHOGENIC/INFECTIOUS PROTEINS | Eidgenoessische Technische Hochschule Zuerich (CH) | 2004-05-06 | — | — | EP | disclosed |
| WO-2004007545-A1 | METHOD FOR INDUCING A CONFORMATIONAL TRANSITION IN PROTEINS SUCH AS PATHOGENIC/INFECTIOUS PROTEINS | EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH (CH) | 2004-01-22 | — | — | WO | disclosed |