SCHEMBL8087624

SCHEMBL8087624

CCCCCCCCCCCCCCCC(=O)OP(=O)(OC(=O)CCCCCCCCCCCCCCC)C(OC(=O)CCC(=O)O)C(O)CO

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 5/20 0.49
MAPT P10636 4/20 0.49
LMNA P02545 7/20 0.44
PRKCA P17252 1/20 0.44
PRKCE Q02156 1/20 0.44
PRKCQ Q04759 1/20 0.44
PRKCD Q05655 1/20 0.44
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
KDM4E B2RXH2 1/20 0.43
DUSP3 P51452 1/20 0.43
GMNN O75496 3/20 0.41
NPSR1 Q6W5P4 3/20 0.41
CYP1A2 P05177 2/20 0.41
HSP90AA1 P07900 2/20 0.41
BLM P54132 2/20 0.41
NR1H4 Q96RI1 2/20 0.41
TSHR P16473 2/20 0.41
TP53 P04637 1/20 0.41
CYP2C9 P11712 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2728683 0.79 LMNA (0.50) MAPK1MAPTLMNAPRKCAPRKCE
SCHEMBL4282445 0.79 LMNA (0.50) MAPK1MAPTLMNAPRKCAPRKCE
SCHEMBL7113626 0.76 MAPT (0.50) MAPK1MAPTLMNAPRKCAPRKCE
Succinic Acid SCHEMBL6014571 0.76 MAPK1 (0.54) MAPK1MAPTLMNAPRKCAPRKCE
Succinic Acid SCHEMBL15667959 0.76 MAPK1 (0.54) MAPK1MAPTLMNAPRKCAPRKCE
Succinic Acid SCHEMBL3991390 0.74 MAPT (0.86) MAPK1MAPTLMNAPRKCAPRKCE
SCHEMBL4442105 0.73 FFAR4 (0.55) MAPK1MAPTLMNAPRKCAPRKCE
SCHEMBL10275408 0.73 DGKA (0.56) MAPTPRKCAPRKCEPRKCQPRKCD
SCHEMBL8440393 0.73 MAPT (0.66) MAPK1MAPTLMNAPRKCAPRKCE
SCHEMBL10539866 0.73 MAPT (0.66) MAPK1MAPTLMNAPRKCAPRKCE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1046394-A2 Novel compositions useful for delivering compounds into a cell ImaRx Pharmaceutical Corp. (US) 2000-10-25 EP disclosed