Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 6/20 | 0.45 |
| ▸ | NLRP3 | Q96P20 | 6/20 | 0.45 |
| ▸ | IL1B | P01584 | 5/20 | 0.45 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.40 |
| ▸ | CCNK | O75909 | 1/20 | 0.40 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | CDK9 | P50750 | 1/20 | 0.40 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.40 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | TACR2 | P21452 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | KMT5B | Q4FZB7 | 1/20 | 0.38 |
| ▸ | KMT5C | Q86Y97 | 1/20 | 0.38 |
| ▸ | BPTF | Q12830 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27289122 | 0.93 | KAT2B (0.46) | KAT2BNLRP3IL1BCCNT1CCNK | |
| SCHEMBL27289106 | 0.90 | NLRP3 (0.48) | KAT2BNLRP3IL1B | |
| SCHEMBL27290003 | 0.90 | NLRP3 (0.51) | KAT2BNLRP3IL1BCCNT1CCNK | |
| SCHEMBL30718315 | 0.87 | IL1B (0.55) | KAT2BNLRP3IL1B | |
| SCHEMBL27288792 | 0.87 | IL1B (0.55) | KAT2BNLRP3IL1B | |
| SCHEMBL26093063 | 0.85 | KAT2B (0.50) | KAT2BNLRP3IL1BCCNT1CCNK | |
| SCHEMBL30374596 | 0.85 | KAT2B (0.50) | KAT2BNLRP3IL1BCCNT1CCNK | |
| SCHEMBL26093070 | 0.85 | KAT2B (0.50) | KAT2BNLRP3IL1BCCNT1CCNK | |
| SCHEMBL26114790 | 0.83 | NLRP3 (0.60) | KAT2BNLRP3IL1BCCNT1CCNK | |
| SCHEMBL26114800 | 0.83 | NLRP3 (0.60) | KAT2BNLRP3IL1BCCNT1CCNK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024006559-A1 | MODULATORS OF NLRP3 INFLAMMASOME AND RELATED PRODUCTS AND METHODS | Neumora Therapeutics, Inc. (US) | 2024-01-04 | — | — | WO | disclosed |