Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL1B | P01584 | 13/20 | 0.55 |
| ▸ | NLRP3 | Q96P20 | 7/20 | 0.51 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.44 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.44 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.44 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27288792 | 1.00 | IL1B (0.55) | IL1BNLRP3CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL30718303 | 0.93 | IL1B (0.55) | IL1BNLRP3CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL27288788 | 0.93 | IL1B (0.55) | IL1BNLRP3CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL27289106 | 0.89 | NLRP3 (0.48) | IL1BNLRP3KAT2B | |
| SCHEMBL27289110 | 0.87 | KAT2B (0.45) | IL1BNLRP3KAT2B | |
| SCHEMBL27297264 | 0.87 | IL1B (0.63) | IL1BNLRP3 | |
| SCHEMBL27290003 | 0.87 | NLRP3 (0.51) | IL1BNLRP3KAT2B | |
| SCHEMBL26090390 | 0.86 | IL1B (0.73) | IL1BNLRP3 | |
| SCHEMBL27289522 | 0.86 | IL1B (0.54) | IL1BNLRP3CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL27290026 | 0.85 | IL1B (0.58) | IL1BNLRP3CHRNB2CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024006559-A1 | MODULATORS OF NLRP3 INFLAMMASOME AND RELATED PRODUCTS AND METHODS | Neumora Therapeutics, Inc. (US) | 2024-01-04 | — | — | WO | disclosed |