Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11777786 | 0.86 | LMNA (0.49) | LMNAKDM4ECHRM1 | |
| SCHEMBL395598 | 0.83 | LMNA (0.55) | LMNAKDM4ECHRM1 | |
| SCHEMBL6533794 | 0.80 | LMNA (0.49) | LMNAKDM4ECHRM1ALDH1A1 | |
| SCHEMBL7545236 | 0.78 | LMNA (0.59) | LMNAKDM4ECHRM1ALDH1A1 | |
| SCHEMBL30747701 | 0.78 | LMNA (0.59) | LMNAKDM4ECHRM1ALDH1A1 | |
| SCHEMBL6313804 | 0.77 | LMNA (0.62) | LMNAKDM4ECHRM1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL27329066 | 0.76 | LMNA (0.57) | LMNAKDM4ECHRM1ALDH1A1 | |
| SCHEMBL18607753 | 0.75 | LMNA (0.47) | LMNAKDM4ECHRM1 | |
| SCHEMBL398161 | 0.74 | POLB (0.61) | LMNAKDM4EALDH1A1 | |
| SCHEMBL30421484 | 0.74 | POLB (0.61) | LMNAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1031710-C | Process for preparing quinoline carboxylic acid boric acid anhydride | CHINOIN GYOGYSZER ES VEGYESZET (HU) | 1996-05-01 | — | — | CN | disclosed |
| CN-1013114-B | Amino and the 5-hydroxyl-6 of 5-, 8-two fluoroquinolone antibacterial agent preparation method of composition | WARNER LAMBERT CO (US) | 1991-07-10 | — | — | CN | disclosed |
| CN-88101941-A | Process for preparing quinoline carboxylic acid boric anhydride | — | 1988-10-26 | — | — | CN | disclosed |
| CN-86108942-A | Amino and the 5-hydroxyl-6 as the 5-of antimicrobial drug, 8-two fluoroquinolones | — | 1987-11-04 | — | — | CN | disclosed |