Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7545236 | 1.00 | LMNA (0.59) | LMNAKDM4ECHRM1ALDH1A1P2RX4 | |
| Hydrochloric Acid SCHEMBL27329066 | 0.98 | LMNA (0.57) | LMNAKDM4ECHRM1ALDH1A1P2RX4 | |
| SCHEMBL27324947 | 0.95 | LMNA (0.55) | LMNAKDM4ECHRM1ALDH1A1P2RX4 | |
| Acetic Acid SCHEMBL27339243 | 0.95 | LMNA (0.55) | LMNAKDM4ECHRM1ALDH1A1P2RX4 | |
| Oxalic Acid SCHEMBL27853164 | 0.95 | LMNA (0.55) | LMNAKDM4ECHRM1ALDH1A1P2RX4 | |
| Sulfuric Acid SCHEMBL27334527 | 0.94 | CHRM1 (0.56) | LMNAKDM4ECHRM1 | |
| Toluene SCHEMBL27351014 | 0.92 | LMNA (0.52) | LMNAKDM4ECHRM1ALDH1A1TP53 | |
| SCHEMBL27419767 | 0.91 | CHRM1 (0.54) | LMNAKDM4ECHRM1 | |
| Lactic Acid SCHEMBL27348546 | 0.90 | LMNA (0.50) | LMNAKDM4ECHRM1 | |
| SCHEMBL785178 | 0.87 | AKR1C3 (0.49) | LMNAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11891385-B1 | 1-cyclopropyl-7-(4-((5-(3,5-dichlorobenzylideneamino)-2-thioxo-1,3,4-thiadiazol-3(2H)-yl)methyl)piperazin-1-yl)-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic aci d as an anti-inflammatory compound | King Faisal University (SA) | 2024-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11891385-B1 | 1-cyclopropyl-7-(4-((5-(3,5-dichlorobenzylideneamino)-2-thioxo-1,3,4-thiadiazol-3(2H)-yl)methyl)piperazin-1-yl)-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic aci d as an anti-inflammatory compound | NFKBIA, IL1B, IL1A | LMNA 4445/4885KDM4E 1674/4885CHRM1 1826/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.