Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 4/20 | 0.36 |
| ▸ | F2R | P25116 | 3/20 | 0.34 |
| ▸ | IDH1 | O75874 | 2/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30700399 | 0.85 | MGLL (0.37) | MGLLF2RRORCHTR2BACACB | |
| SCHEMBL30700345 | 0.82 | IDH1 (0.37) | MGLLF2RIDH1SCN9ARORC | |
| SCHEMBL30700769 | 0.82 | MGLL (0.35) | MGLLF2RSCN9ARORCACACB | |
| SCHEMBL27291884 | 0.80 | MGLL (0.37) | MGLLF2RACACB | |
| SCHEMBL27291886 | 0.80 | MGLL (0.37) | MGLLF2RACACB | |
| SCHEMBL30700574 | 0.80 | MGLL (0.37) | MGLLF2RACACB | |
| SCHEMBL21390052 | 0.78 | MGLL (0.62) | MGLL | |
| SCHEMBL21382150 | 0.78 | MGLL (0.62) | MGLL | |
| SCHEMBL30700845 | 0.76 | TRPC6 (0.39) | MGLLF2RSCN9A | |
| SCHEMBL25303105 | 0.75 | SCN9A (0.37) | SCN9AACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4543870-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. Hoffmann-La Roche AG (CH) | 2025-04-30 | — | — | EP | claimed |
| WO-2023247670-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-12-28 | — | — | WO | claimed |
| WO-2023247670-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-12-28 | — | — | WO | disclosed |
| WO-2023247670-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-12-28 | — | — | WO | disclosed |