Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC6 | Q9Y210 | 5/20 | 0.39 |
| ▸ | MGLL | Q99685 | 3/20 | 0.37 |
| ▸ | LIPE | Q05469 | 3/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.35 |
| ▸ | F2R | P25116 | 2/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27291566 | 0.82 | SCN9A (0.41) | MGLLLIPESCN9AF2R | |
| SCHEMBL30699973 | 0.82 | SCN9A (0.41) | MGLLLIPESCN9AF2R | |
| SCHEMBL30700514 | 0.80 | HRH3 (0.43) | TRPC6LIPEPARP10ALDH1A1GAA | |
| SCHEMBL30700368 | 0.79 | MGLL (0.40) | MGLL | |
| SCHEMBL30700399 | 0.77 | MGLL (0.37) | MGLLF2RHSD11B1 | |
| SCHEMBL27291240 | 0.76 | MGLL (0.36) | MGLLSCN9AF2R | |
| SCHEMBL30700145 | 0.76 | CHRNA7 (0.43) | MGLLLIPESCN9A | |
| SCHEMBL30700372 | 0.74 | MGLL (0.42) | MGLLF2RCYP3A4 | |
| SCHEMBL31615784 | 0.72 | DDB1 (0.48) | LIPEALDH1A1MAPTHTT | |
| SCHEMBL30700168 | 0.72 | HRH3 (0.45) | MGLLHSD11B1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023247670-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-12-28 | — | — | WO | disclosed |