Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 2/20 | 0.35 |
| ▸ | ACACA | Q13085 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.33 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27291343 | 0.93 | LTA4H (0.35) | LTA4HMITFTP53NCOA3ACACB | |
| SCHEMBL23588079 | 0.90 | ACACB (0.46) | MITFTP53NCOA3ACACBACACA | |
| SCHEMBL29973090 | 0.86 | MAPK1 (0.38) | MITFTP53NCOA3ACACBACACA | |
| SCHEMBL23578484 | 0.86 | MAPK1 (0.38) | MITFTP53NCOA3ACACBACACA | |
| SCHEMBL31707538 | 0.84 | HCAR2 (0.35) | MITFTP53NCOA3ACACBACACA | |
| SCHEMBL25804667 | 0.84 | SPHK1 (0.43) | MITFTP53NCOA3MAPTSIRT2 | |
| SCHEMBL30689418 | 0.84 | LTA4H (0.41) | LTA4HMITFTP53NCOA3MAPT | |
| SCHEMBL23578218 | 0.83 | SPHK1 (0.47) | — | |
| SCHEMBL23588294 | 0.82 | TP53 (0.39) | MITFTP53NCOA3MAPTSIRT2 | |
| SCHEMBL23588293 | 0.82 | HTT (0.40) | MITFTP53NCOA3MAPTSIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4634167-A1 | SUBSTITUTED PYRIDINES FOR USE IN TREATING OR PREVENTING INFLAMMATORY DISEASES OR DISEASES ASSOCIATED WITH AN UNDESIRABLE IMMUNE RESPONSE | Sitryx Therapeutics Limited (GB) | 2025-10-22 | — | — | EP | disclosed |
| WO-2024127030-A1 | SUBSTITUTED PYRIDINES FOR USE IN TREATING OR PREVENTING INFLAMMATORY DISEASES OR DISEASES ASSOCIATED WITH AN UNDESIRABLE IMMUNE RESPONSE | SITRYX THERAPEUTICS LIMITED (GB) | 2024-06-20 | — | — | WO | disclosed |