SCHEMBL23578484

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL29973090	1.00	MAPK1 (0.38)	MAPK1S1PR1S1PR4S1PR3S1PR5
	SCHEMBL23588079	0.87	ACACB (0.46)	S1PR1S1PR3MAPTTP53MITF
	SCHEMBL27291365	0.86	LTA4H (0.36)	MAPTTP53HTTMITFNCOA3
	SCHEMBL25804667	0.82	SPHK1 (0.43)	S1PR1S1PR4S1PR3S1PR5MAPT
	SCHEMBL23588293	0.82	HTT (0.40)	MAPK1MAPTTP53HTTMITF
	SCHEMBL23578218	0.81	SPHK1 (0.47)	S1PR1S1PR3S1PR5FFAR1
	SCHEMBL23588345	0.81	RAB9A (0.38)	MAPTTP53HDAC4HDAC1HDAC6
	SCHEMBL25804839	0.81	SPHK2 (0.39)	MAPK1MAPTALDH1A1SMN1; SMN2KMT2A
	SCHEMBL31707538	0.81	HCAR2 (0.35)	MAPTTP53MITFNCOA3ALDH1A1
	SCHEMBL23588294	0.80	TP53 (0.39)	MAPK1MAPTTP53HTTMITF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.