Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.38 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23578484 | 1.00 | MAPK1 (0.38) | MAPK1S1PR1S1PR4S1PR3S1PR5 | |
| SCHEMBL23588079 | 0.87 | ACACB (0.46) | S1PR1S1PR3MAPTTP53MITF | |
| SCHEMBL27291365 | 0.86 | LTA4H (0.36) | MAPTTP53HTTMITFNCOA3 | |
| SCHEMBL25804667 | 0.82 | SPHK1 (0.43) | S1PR1S1PR4S1PR3S1PR5MAPT | |
| SCHEMBL23588293 | 0.82 | HTT (0.40) | MAPK1MAPTTP53HTTMITF | |
| SCHEMBL23578218 | 0.81 | SPHK1 (0.47) | S1PR1S1PR3S1PR5FFAR1 | |
| SCHEMBL23588345 | 0.81 | RAB9A (0.38) | MAPTTP53HDAC4HDAC1HDAC6 | |
| SCHEMBL25804839 | 0.81 | SPHK2 (0.39) | MAPK1MAPTALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL31707538 | 0.81 | HCAR2 (0.35) | MAPTTP53MITFNCOA3ALDH1A1 | |
| SCHEMBL23588294 | 0.80 | TP53 (0.39) | MAPK1MAPTTP53HTTMITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4081511-B3 | CARBOXY DERIVATIVES WITH ANTIINFLAMMATORY PROPERTIES | SITRYX THERAPEUTICS LTD (GB) | 2026-03-04 | — | — | EP | disclosed |
| EP-4081511-A1 | CARBOXY DERIVATIVES WITH ANTIINFLAMMATORY PROPERTIES | Sitryx Therapeutics Limited (GB) | 2022-11-02 | — | — | EP | disclosed |