Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTP1 | P09211 | 6/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | ACACA | Q13085 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27291560 | 0.88 | GSTP1 (0.37) | GSTP1ACACBACACACNR1CNR2 | |
| SCHEMBL27291464 | 0.83 | NPC1 (0.41) | ACACBACACAMITFTP53NCOA3 | |
| SCHEMBL27291640 | 0.82 | GSTP1 (0.47) | GSTP1CNR1CNR2FFAR1 | |
| SCHEMBL23578433 | 0.81 | ACACB (0.57) | ACACBACACAMITFTP53NCOA3 | |
| SCHEMBL29844146 | 0.79 | TDP1 (0.50) | GSTP1FFAR1 | |
| SCHEMBL23588172 | 0.79 | TDP1 (0.50) | GSTP1FFAR1 | |
| SCHEMBL30689442 | 0.78 | GSTP1 (0.41) | GSTP1CNR1CNR2FFAR1 | |
| SCHEMBL30689377 | 0.76 | GSTP1 (0.38) | GSTP1CNR1CNR2TP53FFAR1 | |
| SCHEMBL23578438 | 0.76 | ACACB (0.64) | GSTP1ACACBACACAMITFTP53 | |
| SCHEMBL23578421 | 0.75 | MITF (0.41) | GSTP1MITFTP53NCOA3FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024127030-A1 | SUBSTITUTED PYRIDINES FOR USE IN TREATING OR PREVENTING INFLAMMATORY DISEASES OR DISEASES ASSOCIATED WITH AN UNDESIRABLE IMMUNE RESPONSE | SITRYX THERAPEUTICS LIMITED (GB) | 2024-06-20 | — | — | WO | disclosed |