Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | ACACA | Q13085 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31707540 | 0.86 | ACACB (0.38) | NPC1SMN1; SMN2ALDH1A1NPSR1ACACB | |
| SCHEMBL23578433 | 0.86 | ACACB (0.57) | NPC1SMN1; SMN2ALDH1A1ACACBACACA | |
| SCHEMBL27291563 | 0.83 | GSTP1 (0.41) | ACACBACACATP53MITFNCOA3 | |
| SCHEMBL23578438 | 0.82 | ACACB (0.64) | NPC1ACACBACACATP53MITF | |
| SCHEMBL27291369 | 0.81 | MITF (0.43) | NPC1SMN1; SMN2ACACBACACATP53 | |
| SCHEMBL23588315 | 0.78 | TP53 (0.50) | ALDH1A1ACACBACACATP53MITF | |
| SCHEMBL23578251 | 0.78 | MAPT (0.45) | SMN1; SMN2ALDH1A1TP53KDM4EMAPT | |
| SCHEMBL30880252 | 0.76 | ACACB (0.56) | NPC1SMN1; SMN2ACACBACACATP53 | |
| SCHEMBL23578421 | 0.76 | MITF (0.41) | TP53MITFNCOA3 | |
| SCHEMBL23588172 | 0.76 | TDP1 (0.50) | MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4634167-A1 | SUBSTITUTED PYRIDINES FOR USE IN TREATING OR PREVENTING INFLAMMATORY DISEASES OR DISEASES ASSOCIATED WITH AN UNDESIRABLE IMMUNE RESPONSE | Sitryx Therapeutics Limited (GB) | 2025-10-22 | — | — | EP | disclosed |
| WO-2024127030-A1 | SUBSTITUTED PYRIDINES FOR USE IN TREATING OR PREVENTING INFLAMMATORY DISEASES OR DISEASES ASSOCIATED WITH AN UNDESIRABLE IMMUNE RESPONSE | SITRYX THERAPEUTICS LIMITED (GB) | 2024-06-20 | — | — | WO | disclosed |