Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTP1 | P09211 | 7/20 | 0.45 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 6/20 | 0.36 |
| ▸ | PPARD | Q03181 | 4/20 | 0.35 |
| ▸ | PPARG | P37231 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | FPR2 | P25090 | 2/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27291640 | 0.87 | GSTP1 (0.47) | GSTP1CNR2CNR1PPARAPPARG | |
| SCHEMBL27291560 | 0.85 | GSTP1 (0.37) | GSTP1CNR2CNR1MAPT | |
| SCHEMBL30689442 | 0.78 | GSTP1 (0.41) | GSTP1CNR2CNR1PPARGKMT2A | |
| SCHEMBL27291614 | 0.77 | GSTP1 (0.38) | GSTP1CNR2CNR1PPARAPPARD | |
| SCHEMBL31707536 | 0.76 | GSTP1 (0.45) | GSTP1PPARAPPARDPPARGFPR2 | |
| SCHEMBL30689312 | 0.75 | FPR2 (0.43) | GSTP1MAPTFPR2SCN9AFFAR1 | |
| SCHEMBL30689327 | 0.74 | GSTP1 (0.42) | GSTP1MAPTFFAR1 | |
| SCHEMBL31707540 | 0.73 | ACACB (0.38) | MAPTKMT2A | |
| SCHEMBL25801756 | 0.73 | TSHR (0.55) | GSTP1MAPT | |
| SCHEMBL30689377 | 0.73 | GSTP1 (0.38) | GSTP1CNR2CNR1PPARGMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4634167-A1 | SUBSTITUTED PYRIDINES FOR USE IN TREATING OR PREVENTING INFLAMMATORY DISEASES OR DISEASES ASSOCIATED WITH AN UNDESIRABLE IMMUNE RESPONSE | Sitryx Therapeutics Limited (GB) | 2025-10-22 | — | — | EP | disclosed |
| WO-2024127030-A1 | SUBSTITUTED PYRIDINES FOR USE IN TREATING OR PREVENTING INFLAMMATORY DISEASES OR DISEASES ASSOCIATED WITH AN UNDESIRABLE IMMUNE RESPONSE | SITRYX THERAPEUTICS LIMITED (GB) | 2024-06-20 | — | — | WO | disclosed |