Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTP1 | P09211 | 6/20 | 0.45 |
| ▸ | PPARA | Q07869 | 7/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.35 |
| ▸ | PPARD | Q03181 | 6/20 | 0.35 |
| ▸ | PPARG | P37231 | 3/20 | 0.35 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | FPR2 | P25090 | 2/20 | 0.33 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27291640 | 0.77 | GSTP1 (0.47) | GSTP1PPARAPPARGLMNA | |
| SCHEMBL27291637 | 0.76 | GSTP1 (0.45) | GSTP1PPARASCN9APPARDPPARG | |
| SCHEMBL27291614 | 0.68 | GSTP1 (0.38) | GSTP1PPARASCN9APPARDPPARG | |
| SCHEMBL31527945 | 0.67 | PPARD (0.46) | PPARAPPARDLMNATSHRNFKB1 | |
| SCHEMBL30689442 | 0.67 | GSTP1 (0.41) | GSTP1SCN9APPARGFPR2 | |
| SCHEMBL6903315 | 0.64 | ELANE (0.59) | LMNARAB9A | |
| SCHEMBL14173256 | 0.61 | ELANE (0.62) | LMNATSHRNFKB1RAB9ANFKB2 | |
| SCHEMBL14173258 | 0.61 | ELANE (0.62) | LMNATSHRNFKB1RAB9ANFKB2 | |
| SCHEMBL3780946 | 0.61 | ELANE (0.50) | PPARAPPARGLMNATSHR | |
| SCHEMBL29512347 | 0.60 | TDP1 (0.55) | PPARAPPARDPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4634167-A1 | SUBSTITUTED PYRIDINES FOR USE IN TREATING OR PREVENTING INFLAMMATORY DISEASES OR DISEASES ASSOCIATED WITH AN UNDESIRABLE IMMUNE RESPONSE | Sitryx Therapeutics Limited (GB) | 2025-10-22 | — | — | EP | disclosed |