Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CTSD | P07339 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4919154 | 0.86 | GAA (0.32) | GAAALDH1A1KMT2A | |
| SCHEMBL20233444 | 0.85 | GAA (0.34) | GAAALDH1A1KMT2AHDAC6CYP3A4 | |
| SCHEMBL4915642 | 0.81 | GAA (0.41) | GAAALDH1A1KMT2AHDAC6 | |
| SCHEMBL4919165 | 0.80 | GAA (0.35) | GAAALDH1A1KMT2AHDAC6CYP3A4 | |
| SCHEMBL27292832 | 0.79 | GAA (0.34) | GAAALDH1A1KMT2AHDAC6CYP3A4 | |
| SCHEMBL29508220 | 0.78 | KMT2A (0.36) | KMT2A | |
| SCHEMBL12258958 | 0.78 | OPRM1 (0.39) | CYP1A2 | |
| SCHEMBL21565804 | 0.77 | CYP1A2 (0.38) | GAAALDH1A1KMT2ACYP3A4CYP2D6 | |
| SCHEMBL12258966 | 0.77 | TRPV1 (0.35) | — | |
| SCHEMBL19731703 | 0.77 | HPGD (0.38) | GAAALDH1A1KMT2AHDAC6CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080269065-A1 | Conformationally Constrained Analytical Probes | SYNTRIX BIOSYSTEMS, INC. (US) | 2008-10-30 | — | — | US | disclosed |
| US-20080269065-A1 | Conformationally Constrained Analytical Probes | SYNTRIX BIOSYSTEMS, INC. (US) | 2008-10-30 | — | — | US | disclosed |
| US-20080269065-A1 | Conformationally Constrained Analytical Probes | SYNTRIX BIOSYSTEMS, INC. (US) | 2008-10-30 | — | — | US | disclosed |