Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.41 |
| ▸ | PPARG | P37231 | 7/20 | 0.41 |
| ▸ | PPARD | Q03181 | 7/20 | 0.41 |
| ▸ | PPARA | Q07869 | 7/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.41 |
| ▸ | TLR2 | O60603 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | FABP4 | P15090 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Palmitic Acid SCHEMBL28156036 | 0.83 | ALDH1A1 (0.47) | SOAT1ALDH1A1MEN1KMT2AMAPT | |
| Palmitic Acid SCHEMBL5503920 | 0.83 | SOAT1 (0.57) | SOAT1ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL7722672 | 0.81 | GPR35 (0.56) | ALDH1A1MEN1KMT2AMAPTTDP1 | |
| Palmitic Acid SCHEMBL28156034 | 0.80 | PTGDR2 (0.50) | SOAT1ALDH1A1MEN1KMT2AMAPT | |
| Dodecanoate SCHEMBL2177136 | 0.79 | PPARG (0.49) | ALDH1A1MEN1KMT2AGPR84PPARG | |
| Octanoic Acid SCHEMBL8200120 | 0.79 | PPARG (0.49) | ALDH1A1MEN1KMT2AGPR84PPARG | |
| Palmitic Acid SCHEMBL27937097 | 0.79 | PPARG (0.49) | ALDH1A1MEN1KMT2AGPR84PPARG | |
| Decanoic Acid SCHEMBL28551408 | 0.79 | PPARG (0.49) | ALDH1A1MEN1KMT2AGPR84PPARG | |
| Nitrophenolate SCHEMBL28355685 | 0.78 | MEN1 (0.47) | ALDH1A1MEN1KMT2ACES2CES1 | |
| Octanoic Acid SCHEMBL9716530 | 0.77 | GPR84 (0.65) | ALDH1A1MEN1KMT2AMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1045595-C | Process for the preparation of the intermediates used in the synthesis of 3-aminopiperidine derivatives | PFIZER (US) | 1999-10-13 | — | — | CN | disclosed |
| CN-1035944-C | 3-aminopiperidine derivatives and related nitrogen-containing heterocyclic compounds | PFIZER (US) | 1997-09-24 | — | — | CN | disclosed |
| CN-1087083-A | The intermediates preparation of synthetic 3-amino piperidine derivatives | PFIZER (US) | 1994-05-25 | — | — | CN | disclosed |
| CN-1053060-A | 3-aminopiperidine derivatives and related nitrogen-containing heterocycles | PFIZER (US) | 1991-07-17 | — | — | CN | disclosed |