Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 3/20 | 0.45 |
| ▸ | JAK1 | P23458 | 2/20 | 0.45 |
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.35 |
| ▸ | SYK | P43405 | 8/20 | 0.34 |
| ▸ | AXL | P30530 | 1/20 | 0.34 |
| ▸ | MAP4K1 | Q92918 | 2/20 | 0.34 |
| ▸ | MAP4K3 | Q8IVH8 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27298318 | 0.94 | TYK2 (0.44) | TYK2JAK1SYK | |
| SCHEMBL27293384 | 0.93 | TYK2 (0.43) | TYK2JAK1LRRK2 | |
| SCHEMBL27298258 | 0.81 | TYK2 (0.44) | TYK2JAK1LRRK2SYKAXL | |
| SCHEMBL27293373 | 0.79 | JAK1 (0.44) | TYK2JAK1SYKAXL | |
| SCHEMBL27294015 | 0.78 | TYK2 (0.59) | TYK2JAK1LRRK2AXL | |
| SCHEMBL27417191 | 0.76 | JAK3 (0.49) | TYK2JAK1SYKAXL | |
| SCHEMBL27293273 | 0.75 | TYK2 (0.41) | TYK2JAK1LRRK2SYKMAP4K1 | |
| SCHEMBL30923201 | 0.74 | TYK2 (0.51) | TYK2JAK1 | |
| SCHEMBL30923204 | 0.74 | TYK2 (0.51) | TYK2JAK1 | |
| SCHEMBL27293318 | 0.73 | TYK2 (0.44) | TYK2JAK1LRRK2SYKAXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024107658-A2 | INHIBITORS OF TYK2 | VYRNWY THERAPEUTICS, INC. (US) | 2024-05-23 | — | — | WO | disclosed |