Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | TYK2 | P29597 | 1/20 | 0.41 |
| ▸ | SIRT5 | Q9NXA8 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30923307 | 0.90 | NPSR1 (0.45) | ALDH1A1SMN1; SMN2RAB9ANPC1PKM | |
| SCHEMBL27294096 | 0.90 | NPSR1 (0.45) | ALDH1A1SMN1; SMN2RAB9ANPC1PKM | |
| SCHEMBL27291002 | 0.89 | TYK2 (0.45) | PTK2NPSR1HSD17B10TYK2IGF1R | |
| SCHEMBL30923183 | 0.89 | TYK2 (0.45) | PTK2NPSR1HSD17B10TYK2IGF1R | |
| SCHEMBL27294412 | 0.88 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2RAB9ANPC1PKM | |
| SCHEMBL27294058 | 0.88 | TYK2 (0.55) | ALDH1A1SMN1; SMN2RAB9ANPC1PKM | |
| SCHEMBL27292595 | 0.86 | MAPT (0.49) | ALDH1A1SMN1; SMN2PTK2MAPTNPSR1 | |
| SCHEMBL30923248 | 0.86 | MAPT (0.49) | ALDH1A1SMN1; SMN2PTK2MAPTNPSR1 | |
| SCHEMBL27291710 | 0.86 | HSD17B10 (0.42) | ALDH1A1SMN1; SMN2RAB9ANPC1PKM | |
| SCHEMBL27291804 | 0.86 | HSD17B10 (0.42) | ALDH1A1SMN1; SMN2RAB9ANPC1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024107658-A2 | INHIBITORS OF TYK2 | VYRNWY THERAPEUTICS, INC. (US) | 2024-05-23 | — | — | WO | disclosed |