Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.52 |
| ▸ | NPC1 | O15118 | 5/20 | 0.52 |
| ▸ | RAB9A | P51151 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2852050 | 0.88 | L3MBTL1 (0.57) | L3MBTL1SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL20120512 | 0.83 | ALDH1A1 (0.56) | L3MBTL1SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL7658562 | 0.82 | L3MBTL1 (0.68) | L3MBTL1SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL15709327 | 0.81 | L3MBTL1 (0.63) | L3MBTL1SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL21906828 | 0.80 | L3MBTL1 (0.67) | L3MBTL1SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL23693070 | 0.79 | L3MBTL1 (0.62) | L3MBTL1SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL13548728 | 0.79 | L3MBTL1 (0.79) | L3MBTL1SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL3970912 | 0.79 | MEN1 (0.76) | L3MBTL1SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL4814264 | 0.79 | MEN1 (0.76) | L3MBTL1SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL7393652 | 0.79 | MEN1 (0.76) | L3MBTL1SMN1; SMN2NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012057624-A1 | NOVEL BICYCLIC PEPTIDE MIMETICS | PEPSCAN SYSTEMS B.V. (NL) | 2012-05-03 | — | — | WO | disclosed |
| WO-2012057624-A1 | NOVEL BICYCLIC PEPTIDE MIMETICS | PEPSCAN SYSTEMS B.V. (NL) | 2012-05-03 | — | — | WO | disclosed |