Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 8/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17320654 | 0.83 | GPR35 (0.53) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL25385922 | 0.78 | S100A4 (0.41) | ERN1MAPTMEN1KMT2AHTT | |
| SCHEMBL29404173 | 0.78 | HTT (0.40) | ALDH1A1MAPTHTTL3MBTL1MAPK1 | |
| SCHEMBL4144580 | 0.76 | ERN1 (0.69) | ERN1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL22835493 | 0.76 | SNCA (0.37) | ERN1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL27295454 | 0.73 | HTT (0.32) | ERN1HTT | |
| SCHEMBL13485503 | 0.73 | GPR35 (0.36) | GPR35 | |
| SCHEMBL31056424 | 0.72 | HPGD (0.32) | ERN1MAPTMEN1KMT2AHTT | |
| SCHEMBL17311198 | 0.72 | TTR (0.50) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL10658982 | 0.72 | BACE1 (0.41) | ALDH1A1MAPTMEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024107658-A2 | INHIBITORS OF TYK2 | VYRNWY THERAPEUTICS, INC. (US) | 2024-05-23 | — | — | WO | disclosed |