Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | S100A4 | P26447 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.35 |
| ▸ | GABRP | O00591 | 2/20 | 0.35 |
| ▸ | GABRD | O14764 | 2/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.35 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.35 |
| ▸ | GABRE | P78334 | 2/20 | 0.35 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.35 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.35 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.35 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25385922 | 0.87 | S100A4 (0.41) | HTTS100A4TRPV1GABRPGABRD | |
| SCHEMBL17395909 | 0.81 | TDP1 (0.51) | HTTP2RY6IDO1MAPTCYP3A4 | |
| SCHEMBL20328777 | 0.81 | TSHR (0.53) | HTTMAPTCYP3A4TSHRALDH1A1 | |
| SCHEMBL44775 | 0.81 | MAPK1 (0.51) | HTTMAPTMAPK1TSHRALDH1A1 | |
| SCHEMBL10658982 | 0.81 | BACE1 (0.41) | HTTMAPTPKMMAPK1TSHR | |
| SCHEMBL27295437 | 0.78 | ERN1 (0.49) | HTTMAPTMAPK1ALDH1A1L3MBTL1 | |
| SCHEMBL28092024 | 0.78 | S100A4 (0.41) | S100A4TRPV1MAPTPKMMAPK1 | |
| SCHEMBL17395915 | 0.77 | ALDH1A1 (0.41) | HTTMAPTMAPK1CYP3A4TSHR | |
| SCHEMBL2476070 | 0.77 | NPC1 (0.47) | HTTMAPTMAPK1ALDH1A1RAB9A | |
| SCHEMBL5486010 | 0.76 | HTT (0.44) | HTTMAPTPKMALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022053567-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA CROP PROTECTION AG (CH) | 2022-03-17 | — | — | WO | disclosed |