Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.43 |
| ▸ | LTB4R | Q15722 | 7/20 | 0.43 |
| ▸ | LTB4R2 | Q9NPC1 | 7/20 | 0.43 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | RXRG | P48443 | 1/20 | 0.39 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.38 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8564257 | 0.86 | LTB4R (0.44) | L3MBTL1FFAR4LTB4RLTB4R2PTGER1 | |
| SCHEMBL27300408 | 0.83 | LTB4R (0.54) | FFAR4LTB4RLTB4R2PTGER1RXRA | |
| SCHEMBL6902570 | 0.78 | LTB4R (0.52) | LTB4RLTB4R2 | |
| SCHEMBL8561280 | 0.77 | LTB4R (0.51) | LTB4RLTB4R2 | |
| SCHEMBL6757535 | 0.76 | LTB4R (0.50) | LTB4RLTB4R2 | |
| SCHEMBL6756183 | 0.75 | LTB4R (0.48) | LTB4RLTB4R2 | |
| SCHEMBL8568443 | 0.74 | LTB4R (0.77) | FFAR4LTB4RLTB4R2PTGER1FFAR1 | |
| Iodide SCHEMBL8565212 | 0.73 | LTB4R (0.47) | LTB4RLTB4R2 | |
| SCHEMBL8566998 | 0.73 | LTB4R (0.56) | LTB4RLTB4R2 | |
| SCHEMBL6759116 | 0.73 | NR1H4 (0.47) | LTB4RLTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1035001-C | Substituted phenyl phenol leukotriene antagonists | LILLY CO ELI (US) | 1997-05-28 | — | — | CN | disclosed |