Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Ethylbenzene. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.70 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | FDPS | P14324 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CETP | P11597 | 4/20 | 0.47 |
| ▸ | SRC | P12931 | 1/20 | 0.47 |
| ▸ | LAP3 | P28838 | 3/20 | 0.47 |
| ▸ | ANPEP | P15144 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ACP3 | P15309 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylbenzene SCHEMBL7043912 | 1.00 | TP53 (0.70) | TP53TSHRCYP2C19SMN1; SMN2FDPS | |
| Ethylbenzene SCHEMBL31175848 | 1.00 | TP53 (0.70) | TP53TSHRCYP2C19SMN1; SMN2FDPS | |
| Phosphoric Acid SCHEMBL28176643 | 0.87 | SMN1; SMN2 (0.59) | TP53CYP2C19SMN1; SMN2ALDH1A1SRC | |
| Ethylbenzene SCHEMBL216251 | 0.87 | TP53 (0.93) | TP53TSHRSMN1; SMN2ALDH1A1 | |
| Ethylbenzene SCHEMBL28056495 | 0.87 | TP53 (0.93) | TP53TSHRSMN1; SMN2ALDH1A1 | |
| Ethylbenzene SCHEMBL28009971 | 0.87 | TP53 (0.93) | TP53TSHRSMN1; SMN2ALDH1A1 | |
| Ethylbenzene SCHEMBL9474534 | 0.87 | TP53 (0.93) | TP53TSHRSMN1; SMN2ALDH1A1 | |
| Ethylbenzene SCHEMBL5552776 | 0.85 | TP53 (0.70) | TP53TSHRCYP2C19SMN1; SMN2ALDH1A1 | |
| Ethylbenzene SCHEMBL5460199 | 0.85 | TP53 (0.70) | TP53TSHRCYP2C19SMN1; SMN2ALDH1A1 | |
| Ethylbenzene SCHEMBL27323077 | 0.84 | TP53 (0.78) | TP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108682495-A | A kind of dynamic FFC wire rod hot melt adhesive films of snap connector high temperature anti-current | 广东莱尔新材料科技股份有限公司 | 2018-10-19 | — | — | CN | claimed |
| CN-108485576-A | A kind of heat resistance hot melt adhesive film suitable for round wires conductor FFC wire rods | 广东莱尔新材料科技股份有限公司 | 2018-09-04 | — | — | CN | claimed |
| CN-115398342-A | Film-forming composition | 日产化学株式会社 | 2022-11-25 | — | — | CN | disclosed |
| CN-108682495-A | A kind of dynamic FFC wire rod hot melt adhesive films of snap connector high temperature anti-current | 广东莱尔新材料科技股份有限公司 | 2018-10-19 | — | — | CN | disclosed |
| CN-108586701-A | A kind of binder of hot melt adhesive film and preparation method thereof and its FFC wire rods application | 广东莱尔新材料科技股份有限公司 | 2018-09-28 | — | — | CN | disclosed |
| CN-108485576-A | A kind of heat resistance hot melt adhesive film suitable for round wires conductor FFC wire rods | 广东莱尔新材料科技股份有限公司 | 2018-09-04 | — | — | CN | disclosed |
| CN-1072236-C | Aromatic polycarbonate composition | GE PLASTICS JAPAN LTD (JP) | 2001-10-03 | — | — | CN | disclosed |
| CN-1161346-A | Aromatic polycarbonate composition | GE PLASTICS JAPAN LTD (JP) | 1997-10-08 | — | — | CN | disclosed |
| CN-1035618-C | Process for producing aromatic polycarbonate | GE PLASTICS JAPAN LTD (JP) | 1997-08-13 | — | — | CN | disclosed |
| CN-1053246-A | Process for producing aromatic polycarbonate | GE PLASTICS JAPAN LTD (JP) | 1991-07-24 | — | — | CN | disclosed |