Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | SRC | P12931 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | PLK1 | P53350 | 1/20 | 0.54 |
| ▸ | LPL | P06858 | 1/20 | 0.50 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL27433800 | 0.88 | SMN1; SMN2 (0.50) | SMN1; SMN2CYP2C19SRCALDH1A1PLK1 | |
| Ethylbenzene SCHEMBL31175848 | 0.87 | TP53 (0.70) | SMN1; SMN2CYP2C19SRCALDH1A1TP53 | |
| Ethylbenzene SCHEMBL27296172 | 0.87 | TP53 (0.70) | SMN1; SMN2CYP2C19SRCALDH1A1TP53 | |
| Ethylbenzene SCHEMBL7043912 | 0.87 | TP53 (0.70) | SMN1; SMN2CYP2C19SRCALDH1A1TP53 | |
| SCHEMBL11304410 | 0.85 | ENPP2 (0.60) | SMN1; SMN2CYP2C19SRCALDH1A1PLK1 | |
| SCHEMBL968796 | 0.85 | LMNA (0.56) | SMN1; SMN2CYP2C19SRCALDH1A1PLK1 | |
| SCHEMBL344618 | 0.85 | SMN1; SMN2 (0.52) | SMN1; SMN2CYP2C19SRCALDH1A1PLK1 | |
| SCHEMBL24129428 | 0.83 | SMN1; SMN2 (0.55) | SMN1; SMN2CYP2C19SRCALDH1A1PLK1 | |
| SCHEMBL3399311 | 0.83 | SMN1; SMN2 (0.50) | SMN1; SMN2CYP2C19SRCALDH1A1PLK1 | |
| SCHEMBL27667020 | 0.83 | SMN1; SMN2 (0.66) | SMN1; SMN2CYP2C19SRCALDH1A1PLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109264719-B | Carbon sulfide material and preparation method thereof | 中南大学 | 2020-07-31 | — | — | CN | claimed |
| CN-109536033-A | A kind of preparation method of flame-proof abrasion-resistant bearing material | 江苏立新材料科技有限公司 | 2019-03-29 | — | — | CN | claimed |
| CN-109504149-A | A kind of preparation method of flame-proof abrasion-resistant bearing slurry | 江苏立新材料科技有限公司 | 2019-03-22 | — | — | CN | claimed |
| CN-109504148-A | A kind of abrasion-resistant bearing materials | 江苏立新材料科技有限公司 | 2019-03-22 | — | — | CN | claimed |
| CN-109467927-A | A kind of flame-proof abrasion-resistant bearing slurry | 江苏立新材料科技有限公司 | 2019-03-15 | — | — | CN | claimed |
| CN-109467926-A | Wear-resisting slurry is preparing the application in abrasion-resistant bearing materials | 江苏立新材料科技有限公司 | 2019-03-15 | — | — | CN | claimed |
| CN-109456679-A | A kind of anti-friction bearing slurry | 江苏立新材料科技有限公司 | 2019-03-12 | — | — | CN | claimed |
| CN-109401606-A | Flame-retardant slurry is preparing the application in flame-proof abrasion-resistant bearing material | 江苏立新材料科技有限公司 | 2019-03-01 | — | — | CN | claimed |
| CN-109401592-A | A kind of preparation method of abrasion-resistant bearing materials | 江苏立新材料科技有限公司 | 2019-03-01 | — | — | CN | claimed |
| CN-109385203-A | A kind of flame-proof abrasion-resistant bearing material | 江苏立新材料科技有限公司 | 2019-02-26 | — | — | CN | claimed |
| CN-109385202-A | A kind of preparation method of anti-friction bearing slurry | 江苏立新材料科技有限公司 | 2019-02-26 | — | — | CN | claimed |
| CN-109264719-A | A kind of vulcanization carbon material and preparation method thereof | 中南大学 | 2019-01-25 | — | — | CN | claimed |
| CN-107383764-A | Composite low-heat-conduction material and preparation method thereof | 嘉兴立新材料有限公司 | 2017-11-24 | — | — | CN | claimed |
| CN-107298857-A | A kind of halogen-free flame-resistant electronic material and preparation method thereof | 苏州益可泰电子材料有限公司 | 2017-10-27 | — | — | CN | claimed |
| CN-107222884-A | A kind of communication base station integration testing switch-box | 苏州永安丰新能源科技有限公司 | 2017-09-29 | — | — | CN | claimed |
| CN-122070270-A | Composition comprising 1, 3-tetrafluoropropene, method for the production thereof and use thereof | 科慕埃弗西有限公司 | 2026-05-19 | — | — | CN | disclosed |
| CN-109264719-B | Carbon sulfide material and preparation method thereof | 中南大学 | 2020-07-31 | — | — | CN | disclosed |
| CN-107298857-A | A kind of halogen-free flame-resistant electronic material and preparation method thereof | 苏州益可泰电子材料有限公司 | 2017-10-27 | — | — | CN | disclosed |
| CN-107298857-A | A kind of halogen-free flame-resistant electronic material and preparation method thereof | 苏州益可泰电子材料有限公司 | 2017-10-27 | — | — | CN | disclosed |
| CN-107222884-A | A kind of communication base station integration testing switch-box | 苏州永安丰新能源科技有限公司 | 2017-09-29 | — | — | CN | disclosed |