Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ADH1B | P00325 | 1/20 | 0.33 |
| ▸ | ADH1C | P00326 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propionaldehyde SCHEMBL27524950 | 0.87 | TDP1 (0.53) | ALDH1A1MAPK1TDP1NFE2L2KMT2A | |
| Fluorobenzene SCHEMBL29242128 | 0.84 | NFE2L2 (0.44) | ALDH1A1TDP1NFE2L2KMT2ATSHR | |
| Propionaldehyde SCHEMBL27524952 | 0.82 | ALDH1A1 (0.47) | ALDH1A1MAPK1TDP1NFE2L2HSD17B10 | |
| Fluorobenzene SCHEMBL5606701 | 0.81 | NFE2L2 (0.46) | ALDH1A1MAPK1TDP1NFE2L2KMT2A | |
| Fluorobenzene SCHEMBL27617521 | 0.81 | TP53 (0.45) | MAPK1TDP1NFE2L2KMT2ATSHR | |
| Biphenyl SCHEMBL27273593 | 0.79 | ALDH1A1 (0.50) | ALDH1A1MAPK1TDP1TSHRTP53 | |
| Fluorobenzene SCHEMBL27288992 | 0.78 | NFE2L2 (0.48) | ALDH1A1MAPK1TDP1NFE2L2KMT2A | |
| Fluorobenzene SCHEMBL27600852 | 0.78 | TP53 (0.43) | ALDH1A1MAPK1TDP1NFE2L2KMT2A | |
| Fluorobenzene SCHEMBL27568171 | 0.78 | — | — | |
| Benzene SCHEMBL870097 | 0.78 | ALDH1A1 (0.75) | ALDH1A1MAPK1TDP1TSHRTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106083763-A | Chalcone derivative and preparation method and application | 广西大学 | 2016-11-09 | — | — | CN | claimed |
| CN-106008400-A | New chalcone derivative, preparation method and application thereof in autoimmune diseases | 云南省中医医院 | 2016-10-12 | — | — | CN | claimed |
| CN-102858757-B | Process for preparing divinylarene dioxides | DOW GLOBAL TECHNOLOGIES INC | 2015-07-22 | — | — | CN | claimed |
| CN-102892814-A | Production method for fluorine-containing copolymer composition, coating composition, molded article and article having coating film | ASAHI GLASS CO LTD | 2013-01-23 | — | — | CN | claimed |
| CN-102869653-A | Process for preparing divinylarene dioxides | DOW GLOBAL TECHNOLOGIES LLC | 2013-01-09 | — | — | CN | claimed |
| CN-102858757-A | Process for preparing divinylarene dioxides | DOW GLOBAL TECHNOLOGIES | 2013-01-02 | — | — | CN | claimed |
| CN-1174970-C | Method of preparing 3-haloalkyl-1H-pyrazoles | G��D��ɪ����˾ | 2004-11-10 | — | — | CN | claimed |
| CN-1190960-A | Method of preparing 3-haloalkyl-1H-pyrazoles | SEARLE & CO (US) | 1998-08-19 | — | — | CN | claimed |
| CN-106117113-B | Polysubstituted carbazole, derivative and its synthetic method | 湘潭大学 | 2019-08-16 | — | — | CN | disclosed |
| CN-107235990-B | Polysubstituted indoles bithiophene and derivative and its synthetic method | 湘潭大学 | 2019-01-29 | — | — | CN | disclosed |
| CN-105916866-B | Process for producing cyclobutanetetracarboxylic acid derivative | 日产化学工业株式会社 | 2018-08-28 | — | — | CN | disclosed |
| CN-108250236-A | α-hydroxyl phosphate preparation method based on double β-di-imidogen divalent ytterbium complex | 苏州大学 | 2018-07-06 | — | — | CN | disclosed |
| CN-105665023-B | Application of bis β -diimine bivalent ytterbium complex | 苏州大学 | 2018-06-29 | — | — | CN | disclosed |
| CN-107930688-A | The method that a kind of mesoporous supported imidazole ion liquid catalyst and catalysis oxidation alcohol prepare aldehydes or ketones | 三峡大学 | 2018-04-20 | — | — | CN | disclosed |
| CN-1254337-A | N-hydroxy 4-sulfonylbutyramide compounds | MONSANTO CO (US) | 2000-05-24 | — | — | CN | disclosed |
| CN-1253474-A | Sulfonyl divalent aryl or heteroaryl hydroxamic acid compounds | MONSANTO CO (US) | 2000-05-17 | — | — | CN | disclosed |
| CN-1202828-A | Substituted pyrzolyl benzenesulfonanides for use in veterinary | SEARLE & CO (US) | 1998-12-23 | — | — | CN | disclosed |
| CN-1159446-A | Triazole derivatives, process for preparing the same and drugs containing the same as the active ingredient | SS PHARMACEUTICAL CO (JP) | 1997-09-17 | — | — | CN | disclosed |
| CN-1131146-A | Process for producing N- [1- (2, 4-dichlorophenyl) ethyl ] -2-cyano-3, 3-dimethylbutanamide | SUMITOMO CHEMICAL CO (JP) | 1996-09-18 | — | — | CN | disclosed |
| CN-1036276-A | Make the method for erect image and negative-appearing image with the static main leaf of photo-hardening | DU PONT (US) | 1989-10-11 | — | — | CN | disclosed |