Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 11/20 | 0.73 |
| ▸ | HPGD | P15428 | 3/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.54 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.54 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.54 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.54 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.54 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2729939 | 1.00 | TRPM8 (0.73) | TRPM8HPGDPOLBKDM4EALDH1A1 | |
| SCHEMBL28408661 | 0.85 | TRPM8 (1.00) | TRPM8HPGDKDM4EALDH1A1CYP3A4 | |
| SCHEMBL10270783 | 0.85 | TRPM8 (1.00) | TRPM8HPGDKDM4EALDH1A1CYP3A4 | |
| SCHEMBL10270782 | 0.84 | TRPM8 (1.00) | TRPM8HPGDCYP3A4RAB9AGABRA1 | |
| SCHEMBL2730551 | 0.81 | SNCA (0.47) | TRPM8HPGDPOLBKDM4EALDH1A1 | |
| SCHEMBL2729869 | 0.81 | TRPM8 (1.00) | TRPM8HPGDKDM4EALDH1A1CYP3A4 | |
| SCHEMBL2730618 | 0.81 | TRPM8 (0.75) | TRPM8HPGDKDM4EALDH1A1CYP3A4 | |
| SCHEMBL30582799 | 0.81 | SNCA (0.47) | TRPM8HPGDPOLBKDM4EALDH1A1 | |
| SCHEMBL2730615 | 0.81 | TRPM8 (0.75) | TRPM8HPGDKDM4EALDH1A1CYP3A4 | |
| SCHEMBL2729866 | 0.81 | TRPM8 (1.00) | TRPM8HPGDKDM4EALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025132323-A1 | COMPOSITIONS COMPRISING A SUNSCREEN ACTIVE AGENT | DSM-FIRMENICH AG (CH) | 2025-06-26 | — | — | WO | disclosed |
| CN-118697922-A | Perfume dispersing device | 弗门尼舍有限公司 | 2024-09-27 | — | — | CN | disclosed |
| CN-109414048-B | Coated yeast formulation | 弗门尼舍有限公司 | 2023-09-01 | — | — | CN | disclosed |
| US-11234450-B2 | Preparations having a cooling effect | SYMRISE AG (DE) | 2022-02-01 | — | — | US | disclosed |
| US-10953007-B2 | Compounds useful as modulators of TRPM8 | FIRMENICH INCORPORATED (US) | 2021-03-23 | — | — | US | disclosed |
| EP-3470407-A1 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | Senomyx, Inc. (US) | 2019-04-17 | — | — | EP | disclosed |
| US-10182584-B2 | Cooling preparations | SYMRISE AG (DE) | 2019-01-22 | — | — | US | disclosed |
| US-10016418-B2 | Compounds useful as modulators of TRPM8 | Seaomyx, Inc. (US) | 2018-07-10 | — | — | US | disclosed |
| US-10016418-B2 | Compounds useful as modulators of TRPM8 | Seaomyx, Inc. (US) | 2018-07-10 | — | — | US | disclosed |
| US-20180055069-A1 | PREPARATIONS | SYMRISE AG (DE) | 2018-03-01 | — | — | US | disclosed |
| US-9394287-B2 | Compounds useful as modulators of TRPM8 | SENOMYX, INC. (US) | 2016-07-19 | — | — | US | disclosed |
| US-9394287-B2 | Compounds useful as modulators of TRPM8 | SENOMYX, INC. (US) | 2016-07-19 | — | — | US | disclosed |
| US-20150313820-A1 | PREPARATIONS | SYMRISE AG (DE) | 2015-11-05 | — | — | US | disclosed |
| US-20150313820-A1 | PREPARATIONS | SYMRISE AG (DE) | 2015-11-05 | — | — | US | disclosed |
| EP-2635572-A2 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | Senomyx, Inc. (US) | 2013-09-11 | — | — | EP | disclosed |
| CN-103201279-A | Compounds useful as modulators of TRPM8 | SENOMYX INC | 2013-07-10 | — | — | CN | disclosed |
| WO-2012061698-A9 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | SENOMYX, INC. (US) | 2012-09-13 | — | — | WO | disclosed |
| WO-2012061698-A9 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | SENOMYX, INC. (US) | 2012-09-13 | — | — | WO | disclosed |
| WO-2012061698-A2 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | SENOMYX, INC. (US) | 2012-05-10 | — | — | WO | disclosed |
| WO-2012061698-A2 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | SENOMYX, INC. (US) | 2012-05-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10953007-B2 | Compounds useful as modulators of TRPM8 | TRPM8, TRPM7, TRPM6 | TRPM8 1/4885HPGD 1694/4885POLB 4439/4885 |
| US-11234450-B2 | Preparations having a cooling effect | CRAT, CPT2, CPT1A | TRPM8 60/4885HPGD 2629/4885POLB 1521/4885 |
| US-10016418-B2 | Compounds useful as modulators of TRPM8 | TRPM8, TRPM7, TRPM6 | TRPM8 1/4885HPGD 1694/4885POLB 4439/4885 |
| US-10182584-B2 | Cooling preparations | CRAT, ACAT2, TAS2R50 | TRPM8 62/4885HPGD 2379/4885POLB 1528/4885 |
| US-20180055069-A1 | PREPARATIONS | CRAT, ACAT2, TAS2R50 | TRPM8 101/4885HPGD 2263/4885POLB 1657/4885 |
| US-20150313820-A1 | PREPARATIONS | CRAT, ACAT2, TAS2R50 | TRPM8 101/4885HPGD 2263/4885POLB 1657/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.