Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | P2RX3 | P56373 | 8/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | ACVR1B | P36896 | 1/20 | 0.40 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.40 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.40 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31473369 | 0.90 | FAAH (0.47) | P2RX3L3MBTL1RXRBNAMPT | |
| SCHEMBL27295443 | 0.90 | FAAH (0.47) | P2RX3L3MBTL1RXRBNAMPT | |
| SCHEMBL27300364 | 0.85 | GRM2 (0.43) | GAAL3MBTL1NAMPT | |
| SCHEMBL31473430 | 0.85 | SCN9A (0.47) | L3MBTL1NAMPT | |
| SCHEMBL27295180 | 0.85 | SCN9A (0.47) | L3MBTL1NAMPT | |
| SCHEMBL30392991 | 0.84 | CARM1 (0.45) | L3MBTL1NAMPT | |
| SCHEMBL27299801 | 0.82 | EGLN1 (0.43) | GAAL3MBTL1NAMPT | |
| SCHEMBL27299882 | 0.82 | EGLN1 (0.42) | GAAL3MBTL1NAMPT | |
| SCHEMBL27299733 | 0.81 | SCN9A (0.46) | L3MBTL1NAMPT | |
| SCHEMBL27300452 | 0.81 | L3MBTL1 (0.43) | GAAL3MBTL1NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024029489-A1 | KIT INHIBITORS, COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF | MODULUS DISCOVERY, INC. (JP) | 2024-02-08 | — | — | WO | disclosed |