Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.45 |
| ▸ | HTR3B | O95264 | 2/20 | 0.45 |
| ▸ | HTR3A | P46098 | 2/20 | 0.45 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.45 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | TERT | O14746 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2298661 | 0.85 | MEN1 (0.48) | PARP1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL10679757 | 0.82 | MEN1 (0.42) | PARP1MEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL27930676 | 0.81 | TPMT (0.37) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL27687143 | 0.80 | PARP1 (0.46) | PARP1MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL27608065 | 0.79 | PARP1 (0.47) | PARP1MEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL27337277 | 0.79 | EPHX1 (0.49) | PARP1MEN1KMT2AIKBKB | |
| SCHEMBL27605662 | 0.79 | PARP1 (0.47) | PARP1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL27928000 | 0.79 | CYP1A2 (0.35) | SMN1; SMN2HSD17B10LMNAKDM4ERAB9A | |
| SCHEMBL27639755 | 0.77 | PRSS1 (0.44) | IKBKB | |
| SCHEMBL27345973 | 0.77 | NPC1 (0.50) | MEN1KMT2AMAPTALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104610222-A | Process for preparing episulfide compounds | ASAHI KASEI CHEMICALS CORP | 2015-05-13 | — | — | CN | disclosed |
| CN-103476764-A | Process for producing episulfide compound | ASAHI KASEI CHEMICALS CORP (JP) | 2013-12-25 | — | — | CN | disclosed |
| CN-101463246-B | Heat-sensitive adhesive and heat-sensitive adhesive material | RICOH CO LTD | 2013-10-16 | — | — | CN | disclosed |
| CN-1926121-B | Thiazole derivatives and uses thereof | MERCK SERONO SA | 2012-06-13 | — | — | CN | disclosed |
| CN-102285936-A | 4-thiazolidone carboxylic acid derivative and preparation method and application thereof | — | 2011-12-21 | — | — | CN | disclosed |
| CN-1926121-A | Thiazole derivatives and uses thereof | APPLIED RESEARCH SYSTEMS (AN) | 2007-03-07 | — | — | CN | disclosed |
| CN-1035253-C | Pyranyl cyanoguanidine derivatives | SQUIBB & SONS INC (US) | 1997-06-25 | — | — | CN | disclosed |
| CN-1064272-A | PYRANYL CYANOGUANIDINE DERIVATIVES | SQUIBB & SONS INC (US) | 1992-09-09 | — | — | CN | disclosed |
| CN-86103798-A | The preparation method of N-phenyl-4-phenyl-1-piperazine carbonamidine and their purposes as anti-arrhythmic | — | 1987-06-10 | — | — | CN | disclosed |