Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | KCNN4 | O15554 | 4/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.38 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.38 |
| ▸ | IKBKB | O14920 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28248610 | 0.82 | EPHX1 (0.42) | EPHX1PARP1KCNN4CES2CES1 | |
| SCHEMBL27687143 | 0.80 | PARP1 (0.46) | PARP1MEN1KMT2AIKBKB | |
| SCHEMBL27301554 | 0.79 | PARP1 (0.47) | PARP1MEN1KMT2AIKBKB | |
| SCHEMBL27605662 | 0.79 | PARP1 (0.47) | PARP1HDAC6MEN1KMT2ANR3C2 | |
| SCHEMBL27608065 | 0.79 | PARP1 (0.47) | PARP1MEN1KMT2A | |
| SCHEMBL27928000 | 0.79 | CYP1A2 (0.35) | HDAC1 | |
| SCHEMBL27708208 | 0.78 | KDM4E (0.59) | EPHX1CES2MEN1KMT2A | |
| SCHEMBL27639755 | 0.77 | PRSS1 (0.44) | IKBKB | |
| SCHEMBL27317150 | 0.77 | ALDH1A1 (0.50) | KCNN4CES2CES1HDAC6MEN1 | |
| SCHEMBL158241 | 0.77 | SIRT1 (0.42) | PARP1TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101687816-A | Triaminopyrimidine derivatives as the CDC25 inhibitors of phosphatases | IPSEN PHARMA SAS | 2010-03-31 | — | — | CN | claimed |
| CN-108137528-A | Pleocidin derivative as insecticide | 阿格里麦蒂斯有限责任公司 | 2018-06-08 | — | — | CN | disclosed |
| CN-107235916-A | A kind of licochalcone A deracil analog derivative and its synthetic method for having antitumor activity | 陕西科技大学 | 2017-10-10 | — | — | CN | disclosed |
| CN-104540835-B | The imidazo thiadiazoles derivative as proteinase activated receptors 4 (PAR4) inhibitor for treating platelet aggregation | 百时美施贵宝公司 | 2017-08-08 | — | — | CN | disclosed |
| CN-103476764-B | Process for producing episulfide compound | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2016-05-25 | — | — | CN | disclosed |
| CN-103288721-B | (4-(4-[6-(trifluoromethylpyridin-3-base amino)-containing N heteroaryl]-phenyl)-cyclohexyl)-acetogenin and pharmaceutical use thereof | NOVARTIS AG (CH) | 2016-04-20 | — | — | CN | disclosed |
| CN-104610222-A | Process for preparing episulfide compounds | ASAHI KASEI CHEMICALS CORP | 2015-05-13 | — | — | CN | disclosed |
| CN-104540835-A | Imidazothiadiazole derivatives as protease activated receptor 4 (par4) inhibitors for treating platelet aggregation | BRISTOL MYERS SQUIBB CO | 2015-04-22 | — | — | CN | disclosed |
| CN-103476764-A | Process for producing episulfide compound | ASAHI KASEI CHEMICALS CORP (JP) | 2013-12-25 | — | — | CN | disclosed |
| CN-103288721-A | (4-(4-[6-(trifluoromethyl-pyridin-3-ylamino)-n-containing-heteroaryl]-phenyl)-cyclohexyl)-acetic acid derivatives and pharmaceutical uses thereof | NOVARTIS AG | 2013-09-11 | — | — | CN | disclosed |
| CN-101415683-B | Novel compounds | NOVARTIS AG | 2013-07-17 | — | — | CN | disclosed |
| CN-103086981-A | New compounds | NOVARTIS AG | 2013-05-08 | — | — | CN | disclosed |
| CN-102367240-A | 1,2,3-thiadiazole mother ring-contained iminothiazolone compounds, intermediate thereof, and preparation methods and applications of compound and intermediate | UNIV EAST CHINA SCIENCE & TECH | 2012-03-07 | — | — | CN | disclosed |
| CN-101687816-A | Triaminopyrimidine derivatives as the CDC25 inhibitors of phosphatases | IPSEN PHARMA SAS | 2010-03-31 | — | — | CN | disclosed |
| CN-101415683-A | Novel compounds | NOVARTIS AG (CH) | 2009-04-22 | — | — | CN | disclosed |
| CN-1043891-C | Fluorobenzothiazolyloxyacetamides | BAYER AG (DE) | 1999-06-30 | — | — | CN | disclosed |
| CN-1087903-A | Fluoro benzothiazole oxygen yl acetamide | BAYER AG (DE) | 1994-06-15 | — | — | CN | disclosed |