Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | USP7 | Q93009 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TERT | O14746 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2298661 | 0.85 | MEN1 (0.48) | MEN1MAPTKMT2ALMNAHTT | |
| SCHEMBL27301554 | 0.82 | PARP1 (0.47) | MEN1MAPTKMT2ALMNAHTT | |
| SCHEMBL27971556 | 0.80 | HSD17B10 (0.50) | MEN1KMT2ALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL19632078 | 0.79 | LMNA (0.44) | MEN1MAPTKMT2ALMNAHTT | |
| SCHEMBL28037693 | 0.77 | TEAD1 (0.43) | MEN1MAPTKMT2ALMNAHTT | |
| SCHEMBL10431593 | 0.77 | MTNR1A (0.48) | MEN1MAPTKMT2ALMNAALDH1A1 | |
| SCHEMBL28470876 | 0.76 | TERT (0.49) | MEN1MAPTKMT2ALMNAHTT | |
| SCHEMBL28982445 | 0.74 | IDO1 (0.40) | MEN1MAPTKMT2AALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL28845768 | 0.73 | MTNR1A (0.47) | MEN1MAPTKMT2ALMNAALDH1A1 | |
| SCHEMBL25600203 | 0.72 | MAPT (0.41) | MEN1MAPTKMT2ALMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4720503-A | N-substituted fused-heterocyclic carboxamide derivatives as dual cyclooxygenase and lipoxygenase inhibitors | MERCK & CO., INC. (US) | 1988-01-19 | — | — | US | disclosed |