Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.32 |
| ▸ | FYN | P06241 | 2/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | BCR | P11274 | 1/20 | 0.32 |
| ▸ | PRKCA | P17252 | 1/20 | 0.32 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4556812 | 0.72 | CYP19A1 (0.47) | NPC1MAPTRAB9ASMN1; SMN2KDM4E | |
| SCHEMBL25436071 | 0.70 | GRM5 (0.58) | NPC1RAB9ASMN1; SMN2ALDH1A1CYP2A6 | |
| SCHEMBL6677484 | 0.65 | ALDH1A1 (0.50) | NPC1MAPTRAB9AKDM4EMEN1 | |
| SCHEMBL27832176 | 0.62 | MIF (0.63) | NPC1MAPTRAB9AALDH1A1CYP2A6 | |
| SCHEMBL27832175 | 0.62 | FYN (0.53) | NPC1MAPTRAB9ACYP2A6CYP19A1 | |
| SCHEMBL9384083 | 0.61 | KMT2A (0.62) | MAPTSMN1; SMN2KDM4EALDH1A1KMT2A | |
| SCHEMBL27832184 | 0.61 | FYN (0.45) | NPC1MAPTRAB9AKDM4EALDH1A1 | |
| SCHEMBL21634194 | 0.60 | CYP2A6 (0.50) | NPC1MAPTRAB9ASMN1; SMN2KDM4E | |
| SCHEMBL27008244 | 0.60 | CYP2A6 (0.50) | MAPTSMN1; SMN2KDM4EALDH1A1CYP2A6 | |
| SCHEMBL2614253 | 0.60 | CYP2A6 (0.50) | MAPTSMN1; SMN2KDM4EALDH1A1CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2630133-A1 | NOVEL HETEROCYCLIC COMPOUNDS AS PESTICIDES | Bayer Intellectual Property GmbH (DE) | 2013-08-28 | — | — | EP | disclosed |
| WO-2012052412-A1 | NOVEL HETEROCYCLIC COMPOUNDS AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2012-04-26 | — | — | WO | disclosed |