Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 7/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MIF | P14174 | 1/20 | 0.46 |
| ▸ | USP8 | P40818 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.43 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.42 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.42 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.41 |
| ▸ | P4HB | P07237 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27832176 | 0.84 | MIF (0.63) | FYNMAPTMIFUSP8CYP19A1 | |
| SCHEMBL6677484 | 0.82 | ALDH1A1 (0.50) | FYNMAPTMIFUSP8CYP19A1 | |
| SCHEMBL27832171 | 0.80 | GRM5 (0.62) | MAPTCYP19A1CYP11B1CYP11B2 | |
| SCHEMBL27812062 | 0.80 | MAPT (0.53) | FYNMAPTMIFUSP8CYP1A2 | |
| SCHEMBL182177 | 0.80 | CA2 (0.50) | FYNMIFNPC1RAB9APOLB | |
| SCHEMBL182558 | 0.77 | KMO (0.59) | FYNMAPTMIFNPC1RAB9A | |
| SCHEMBL16633967 | 0.76 | MAPT (0.47) | FYNMAPTMIFCYP19A1CYP11B1 | |
| SCHEMBL17477103 | 0.75 | NPC1 (0.47) | MAPTCYP3A4NPC1RAB9ACYP2A6 | |
| SCHEMBL28135004 | 0.75 | NPC1 (0.48) | FYNMAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL27832184 | 0.74 | FYN (0.45) | FYNMAPTMIFUSP8CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102089297-A | Novel 1,2,4 oxadiazole compounds and methods of use thereof | ABBOTT LAB | 2011-06-08 | — | — | CN | disclosed |