Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 8/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27305819 | 0.84 | ALDH1A1 (0.44) | PGRALDH1A1HSD17B10CYP3A4TDP1 | |
| SCHEMBL30663249 | 0.84 | ALDH1A1 (0.44) | PGRALDH1A1HSD17B10CYP3A4TDP1 | |
| SCHEMBL27305898 | 0.82 | ALDH1A1 (0.42) | PGRALDH1A1HSD17B10CYP3A4TDP1 | |
| SCHEMBL27305823 | 0.81 | ALDH1A1 (0.41) | PGRALDH1A1HSD17B10CYP3A4TDP1 | |
| SCHEMBL27305997 | 0.79 | ALDH1A1 (0.36) | PGRALDH1A1HSD17B10CYP3A4TDP1 | |
| SCHEMBL27306478 | 0.77 | APP (0.30) | APP | |
| SCHEMBL27307055 | 0.76 | MGAT1 (0.31) | APPNPSR1 | |
| SCHEMBL27306014 | 0.75 | ALDH1A1 (0.34) | PGRALDH1A1HSD17B10CYP3A4TDP1 | |
| SCHEMBL8856837 | 0.74 | PGR (0.62) | PGRALDH1A1HSD17B10CYP3A4TDP1 | |
| SCHEMBL30973137 | 0.74 | PGR (0.62) | PGRALDH1A1HSD17B10CYP3A4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023235855-A1 | QUINOLINEAMINE ANTIDEGRADANT COMPOUNDS AND USES THEREOF | FLEXSYS AMERICA L.P. (US) | 2023-12-07 | — | — | WO | disclosed |