Cytarabine 5'-Phosphate

Cytarabine 5'-Phosphate

SCHEMBL27306

Nc1ccn([C@@H]2O[C@H](COP(=O)(O)O)[C@@H](O)[C@H]2O)c(=O)n1.O=c1ccn([C@@H]2O[C@H](COP(=O)(O)O)[C@@H](O)[C@H]2O)c(=O)[nH]1.O=c1nc[nH]c2c1ncn2[C@@H]1O[C@H](COP(=O)(O)O)[C@@H](O)[C@H]1O

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
P2RY2 P41231 15/20 0.67
P2RY6 Q15077 11/20 0.59
P2RY4 P51582 9/20 0.59
RNASEL Q05823 2/20 0.57
P2RY14 Q15391 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cytarabine 5'-Phosphate SCHEMBL16516255 0.94 P2RY2 (0.56) P2RY2P2RY6P2RY4
Cytarabine 5'-Phosphate SCHEMBL29359440 0.89 P2RY2 (0.70) P2RY2P2RY6P2RY4RNASEL
Cytarabine 5'-Phosphate SCHEMBL19347100 0.88 P2RY2 (0.85) P2RY2P2RY6P2RY4P2RY14
SCHEMBL184241 0.83 P2RX3 (0.61) P2RY2
SCHEMBL2683124 0.83 P2RX3 (0.61) P2RY2
Cytarabine 5'-Phosphate SCHEMBL29424346 0.82 P2RX3 (0.69) P2RY2
Cytarabine 5'-Phosphate SCHEMBL29356502 0.82 P2RX3 (0.69) P2RY2
Uridine Triphosphate SCHEMBL25298912 0.82 P2RY2 (0.92) P2RY2P2RY6P2RY4P2RY14
SCHEMBL15082664 0.80 P2RY2 (1.00) P2RY2P2RY6P2RY4P2RY14
SCHEMBL25248334 0.80 P2RY2 (0.80) P2RY2P2RY6P2RY4P2RY14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 8352 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260139860-A1 PRODUCTS OF MANUFACTURE FOR THE TREATMENT, PREVENTION AND AMELIORATION OF MICROBIAL INFECTIONS CENTRE FOR DIGESTIVE DISEASES (AU) 2026-05-21 US claimed
EP-4094767-B1 NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO UNIV EMORY (US) 2026-05-20 EP claimed
US-12595280-B2 Phosphoramidates for the treatment of hepatitis B virus EMORY UNIVERSITY (US) 2026-04-07 US claimed
EP-3534910-B1 RIFAMPICIN DERIVATIVES WITH ANTIBACTERIAL ACTIVITY POP TEST ONCOLOGY LLC (US) 2026-03-25 EP claimed
US-20260060964-A1 METHODS AND COMPOSITIONS FOR TREATING SEPSIS ANTIVIRUS THERAPEUTICS (US) 2026-03-05 US claimed
US-20260041660-A1 Compositions And Methods for Treating Acute Respiratory Distress Syndrome (ARDS) And Inflammatory Disorders Caused by Corona Viruses and Other Respiratory Pathogens or Agents That Mediate Pulmonary Injury, Inflammation or Acute Respiratory Distress, And Related Compositions and Methods for Treating and Preventing Human SARS Coronavirus Infection, COVID-19 Disease and Related Symptoms CHANG RICHARD L (US) 2026-02-12 US claimed
EP-4680248-A1 PRODUCTS OF MANUFACTURE AND THERAPEUTIC COMPOSITIONS FOR TREATING, AMELIORATING OR PREVENTING VIRAL INFECTIONS AND METHODS FOR MAKING AND USING THEM Topelia Aust Limited (ACN 652 771 670) (AU) 2026-01-21 EP claimed
EP-4673157-A2 COMPOSITIONS FOR MODULATING GUT MICROFLORA POPULATIONS, TREATMENT OF DYSBIOSIS AND DISEASE PREVENTION, AND METHODS FOR MAKING AND USING SAME Persephone Biosciences, Inc. (US) 2026-01-07 EP claimed
EP-4673568-A1 MICROBIAL BIOMARKERS IN TRANSPLANTATION AND RELATED METHODS Karius, Inc. (US) 2026-01-07 EP claimed
WO-2025264805-A2 SYNBIOTICS FOR MODULATING GUT MICROFLORA POPULATIONS, TREATMENT OF DYSBIOSIS AND DISEASE PREVENTION, AND METHODS FOR MAKING AND USING SAME PERSEPHONE BIOSCIENCES, INC. (US) 2025-12-26 WO claimed
WO-2002085358-A2 ANTIVIRAL AGENTS AND METHODS OF TREATING VIRAL INFECTIONS VION PHARMACEUTICALS, INC. (US) 2002-10-31 WO claimed
CN-1302612-A Process for preparing pharmaceutical composition containing 1, 3-oxathiolane nucleoside analogue IAF BIOCHEM INT (CA) 2001-07-11 CN claimed
EP-1098641-A1 CHEMICALLY INDUCED INTRACELLULAR HYPERTHERMIA Texas Pharmaceuticals, Inc. (US) 2001-05-16 EP claimed
US-6180639-B1 THERAPY FOR HUMAN IMMUNODEFICIENCY VIRUS BIOCHEM PHARMA INC. (CA) 2001-01-30 US claimed
EP-1062950-A2 1,3 Oxathiolane nucleoside analogues BIOCHEM PHARMA INC (CA) 2000-12-27 EP claimed
CN-1057231-C Modulation of AIDS virus-related events by double-stuanded RNAs HEM RES INC (US) 2000-10-11 CN claimed
WO-2000006143-A1 CHEMICALLY INDUCED INTRACELLULAR HYPERTHERMIA TEXAS PHARMACEUTICALS, INC. (US) 2000-02-10 WO claimed
US-5357636-A Flexible protective medical gloves and methods for their use DRESDNER JR KARL P (US) 1994-10-25 US claimed
US-4900548-A AIDS TREATMENT HARVARD UNIVERSITY (US) 1990-02-13 US claimed
EP-0286224-A2 Treatment of human viral infection by dsRNA combined with viral inhibitors HEM PHARMACEUTICALS CORP. (US) 1988-10-12 EP claimed