Cytarabine 5'-Phosphate

Cytarabine 5'-Phosphate

SCHEMBL29356502

Nc1ccn(C2OC(COP(=O)(O)O)C(O)C2O)c(=O)n1.O=c1[nH]cnc2c1ncn2C1OC(COP(=O)(O)O)C(O)C1O

nearest known ligand 0.69

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ P2RX3 P56373 1/20 0.69
▸ TAS1R3 Q7RTX0 3/20 0.60
▸ TAS1R1 Q7RTX1 3/20 0.60
▸ P2RY2 P41231 2/20 0.60
▸ DNPH1 O43598 2/20 0.60
▸ PRKAB2 O43741 1/20 0.60
▸ TRPM2 O94759 1/20 0.60
▸ LDHA P00338 1/20 0.60
▸ ADRB2 P07550 1/20 0.60
▸ FBP1 P09467 1/20 0.60
▸ SRC P12931 1/20 0.60
▸ ADORA1 P30542 1/20 0.60
▸ P2RY1 P47900 1/20 0.60
▸ PRKAG1 P54619 1/20 0.60
▸ PRKAA2 P54646 1/20 0.60
▸ PDE4D Q08499 1/20 0.60
▸ KCNH2 Q12809 1/20 0.60
▸ PRKAA1 Q13131 1/20 0.60
▸ PDE3A Q14432 1/20 0.60
▸ SMN1; SMN2 Q16637 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cytarabine 5'-Phosphate SCHEMBL29424346 1.00 P2RX3 (0.69) P2RX3TAS1R3TAS1R1P2RY2DNPH1
Cytarabine 5'-Phosphate SCHEMBL29359440 0.94 P2RY2 (0.70) P2RX3P2RY2IMPDH2IMPDH1
SCHEMBL29452474 0.93 P2RX3 (0.65) P2RX3TAS1R3TAS1R1P2RY2DNPH1
Cytarabine 5'-Phosphate SCHEMBL29390918 0.92 P2RX3 (0.59) P2RX3TAS1R3TAS1R1P2RY2DNPH1
SCHEMBL24160912 0.89 P2RX3 (0.85) P2RX3TAS1R3TAS1R1P2RY2DNPH1
SCHEMBL12931223 0.89 P2RX3 (0.85) P2RX3TAS1R3TAS1R1P2RY2DNPH1
SCHEMBL12727824 0.89 P2RX3 (0.85) P2RX3TAS1R3TAS1R1P2RY2DNPH1
SCHEMBL184240 0.89 P2RX3 (0.85) P2RX3TAS1R3TAS1R1P2RY2DNPH1
SCHEMBL18258283 0.89 P2RX3 (0.85) P2RX3TAS1R3TAS1R1P2RY2DNPH1
SCHEMBL24377014 0.89 P2RX3 (0.85) P2RX3TAS1R3TAS1R1P2RY2DNPH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 585 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12622922-B2 Compositions and methods for metal containing formulations capable of modulating immune response THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2026-05-12 — — US claimed
US-12622956-B2 Methods and vaccines for inducing immune responses to multiple different MHC molecules Mayo Foundation for Medical Education and Research; (MN) 2026-05-12 — — US claimed
US-20260115281-A1 TRITERPENE SAPONIN ANALOGUES ADJUVANCE TECH INC (US) 2026-04-30 — — US claimed
US-12594291-B2 Intratumoral alpha-emitter radiation and activation of cytoplasmatic sensors for intracellular pathogen ALPHA TAU MEDICAL LTD (IL) 2026-04-07 — — US claimed
US-12569554-B2 Triterpene saponin analogues ADJUVANCE TECHNOLOGIES, INC. (US) 2026-03-10 — — US claimed
US-20260041758-A1 IMMUNIZATION STRATEGIES TO MORE NATURALLY GUIDE THE MATURATION OF ANTIBODIES AGAINST HUMAN IMMMUNODEFICIENCY VIRUS (HIV) IN HIV-INFECTED SUBJECTS FRED HUTCHINSON CANCER CENTER (US) 2026-02-12 — — US claimed
US-12433940-B2 Silicified cell replicas, methods of making, and methods of using UNM RAINFOREST INNOVATIONS (US) 2025-10-07 — — US claimed
EP-3873598-B1 INTRATUMORAL ALPHA-EMITTER RADIATION AND ACTIVATION OF CYTOPLASMATIC SENSORS FOR INTRACELLULAR PATHOGEN ALPHA TAU MEDICAL LTD (IL) 2025-07-02 — — EP claimed
WO-2025137325-A1 IMMUNIZATION SCHEDULES TO ELICIT BROADLY-NEUTRALIZING ANTIBODIES AGAINST HUMAN IMMMUNODEFICIENCY VIRUS (HIV) FRED HUTCHINSON CANCER CENTER (US) 2025-06-26 — — WO claimed
CN-120137897-A PBMC and DC loaded tumor cell antigen peptide immune co-culture method and application 创芯国际生物科技(广州)有限公司 2025-06-13 — — CN claimed
CN-115029311-A Anucleated cell for targeted macrophage delivery and preparation method and application thereof 中国药科大学 2022-09-09 — — CN claimed
US-20220267734-A1 HETEROGENEOUS STEM CELL POPULATION, PREPARATION METHOD THEREFOR AND USE THEREOF INSTITUTE OF BASIC MEDICAL SCIENCES, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) 2022-08-25 — — US claimed
EP-4041295-A1 MULTI-DOMAIN PROTEIN VACCINE Fritsch, Edward (US) 2022-08-17 — — EP claimed
CN-114681612-A Bladder perfusion pharmaceutical composition and preparation method and application thereof 苏州百迈生物医药有限公司 2022-07-01 — — CN claimed
US-20220175926-A1 TARGETED SYNERGISTIC CANCER IMMUNOTHERAPY BRIGHAM & WOMENS HOSPITAL INC (US) 2022-06-09 — — US claimed
US-20220175814-A1 IMMUNOTHERAPY FOR THE TREATMENT OF CANCER TARGIMMUNE THERAPEUTICS AG (CH) 2022-06-09 — — US claimed
EP-3999110-A1 COMPOSITIONS AND METHODS FOR TREATING AUTOIMMUNE DISORDERS The Regents of The University of Michigan (US) 2022-05-25 — — EP claimed
US-20220125835-A1 SILICIFIED IMMUNOGENIC CELLS, METHODS OF MAKING, AND METHODS OF USING UNM RAINFOREST INNOVATIONS 2022-04-28 — — US claimed
US-20220072023-A1 COMPOSITIONS AND METHODS FOR METAL CONTAINING FORMULATIONS CAPABLE OF MODULATING IMMUNE RESPONSE NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2022-03-10 — — US claimed
US-20220040291-A1 HCoV VACCINE FOR IMPROVING IMMUNITY AGAINST SARS-COV-2 INFECTION MOORE TIMOTHY S (US) 2022-02-10 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220072023-A1 COMPOSITIONS AND METHODS FOR METAL CONTAINING FORMULATIONS CAPABLE OF MODULATING IMMUNE RESPONSE MYD88, STING1, TLR3 P2RX3 260/4885TAS1R3 409/4885TAS1R1 385/4885
US-12569554-B2 Triterpene saponin analogues TLR4, TLR7, TLR8 P2RX3 272/4885TAS1R3 2272/4885TAS1R1 3637/4885
US-20260115281-A1 TRITERPENE SAPONIN ANALOGUES NR1H2, NR1H3, LSS P2RX3 2531/4885TAS1R3 3070/4885TAS1R1 2537/4885
US-20220175814-A1 IMMUNOTHERAPY FOR THE TREATMENT OF CANCER TLR3, CD274, PDCD1 P2RX3 3786/4885TAS1R3 1487/4885TAS1R1 1696/4885
US-12622922-B2 Compositions and methods for metal containing formulations capable of modulating immune response STING1, CGAS, TLR3 P2RX3 57/4885TAS1R3 275/4885TAS1R1 525/4885
US-12594291-B2 Intratumoral alpha-emitter radiation and activation of cytoplasmatic sensors for intracellular pathogen STING1, IFNAR1, IFNG P2RX3 2419/4885TAS1R3 1134/4885TAS1R1 763/4885
US-12622956-B2 Methods and vaccines for inducing immune responses to multiple different MHC molecules MICA, MUC1, MYD88 P2RX3 1298/4885TAS1R3 691/4885TAS1R1 1601/4885
US-20260041758-A1 IMMUNIZATION STRATEGIES TO MORE NATURALLY GUIDE THE MATURATION OF ANTIBODIES AGAINST HUMAN IMMMUNODEFICIENCY VIRUS (HIV) IN HIV-INFECTED SUBJECTS CD4, IGSF11, ICOS P2RX3 1345/4885TAS1R3 1167/4885TAS1R1 1868/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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