Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA5 | P31644 | 3/20 | 0.48 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.48 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.48 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.48 |
| ▸ | SLC6A11 | P48066 | 2/20 | 0.48 |
| ▸ | SLC6A13 | Q9NSD5 | 2/20 | 0.48 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.48 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.48 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.48 |
| ▸ | CPN1 | P15169 | 2/20 | 0.39 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.38 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.38 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.38 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL454712 | 0.84 | — | — | |
| Hydrochloric Acid SCHEMBL23199282 | 0.82 | GABRA5 (0.40) | GABRA5GABRB2SLC6A1SLC6A12SLC6A11 | |
| Propionic Acid SCHEMBL27326892 | 0.80 | GABRA5 (0.50) | GABRA5GABRB2SLC6A1SLC6A12SLC6A11 | |
| Propionic Acid SCHEMBL27292897 | 0.78 | GABRA5 (0.48) | GABRA5GABRB2SLC6A1SLC6A12SLC6A11 | |
| Propionic Acid SCHEMBL27349374 | 0.77 | GABRA5 (0.47) | GABRA5GABRB2SLC6A1SLC6A12SLC6A11 | |
| Propionic Acid SCHEMBL16030395 | 0.77 | ITGB3 (0.55) | GABRA5GABRB2SLC6A1SLC6A12SLC6A11 | |
| Propionic Acid SCHEMBL27304995 | 0.76 | GABRA5 (0.46) | GABRA5GABRB2SLC6A1SLC6A12SLC6A11 | |
| Propionic Acid SCHEMBL3790146 | 0.74 | — | — | |
| SCHEMBL44579 | 0.73 | GABRA5 (0.75) | GABRA5GABRB2SLC6A1SLC6A12SLC6A11 | |
| Propionic Acid SCHEMBL27300730 | 0.73 | GABRA5 (0.43) | GABRA5GABRB2SLC6A1SLC6A12SLC6A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1037268-C | Antipicornaviral pyridazinamines | JANSSEM PHARMACEUTICA N V (BE) | 1998-02-04 | — | — | CN | disclosed |