Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27306239 | 0.88 | APP (0.35) | APPNPSR1GAAHPGDLMNA | |
| SCHEMBL27306369 | 0.87 | APP (0.32) | APP | |
| SCHEMBL27306242 | 0.85 | STK10 (0.36) | APPHPGDMAPTMAPK1 | |
| SCHEMBL27306478 | 0.85 | APP (0.30) | APP | |
| SCHEMBL27306481 | 0.80 | — | — | |
| SCHEMBL27306609 | 0.78 | ALDH1A1 (0.34) | HSD17B10 | |
| SCHEMBL27306365 | 0.77 | EGFR (0.37) | NPSR1GAAHPGDLMNAMAPT | |
| SCHEMBL30663249 | 0.77 | ALDH1A1 (0.44) | APPNPSR1GAAHPGDLMNA | |
| SCHEMBL27305819 | 0.77 | ALDH1A1 (0.44) | APPNPSR1GAAHPGDLMNA | |
| SCHEMBL27306826 | 0.75 | NPSR1 (0.33) | APPNPSR1GAAHPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023235855-A1 | QUINOLINEAMINE ANTIDEGRADANT COMPOUNDS AND USES THEREOF | FLEXSYS AMERICA L.P. (US) | 2023-12-07 | — | — | WO | disclosed |