Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STK10 | O94804 | 4/20 | 0.36 |
| ▸ | SLK | Q9H2G2 | 4/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | BRAF | P15056 | 1/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 5/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | RAD52 | P43351 | 1/20 | 0.30 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27306239 | 0.85 | APP (0.35) | EGFRSRCMEN1KMT2AAPP | |
| SCHEMBL27306358 | 0.85 | APP (0.32) | APPMAPTHPGDMAPK1 | |
| SCHEMBL27306816 | 0.84 | ALDH1A1 (0.38) | NR3C1EGFRMEN1KMT2AMAPT | |
| SCHEMBL27306369 | 0.84 | APP (0.32) | STK10SLKGSK3BAPP | |
| SCHEMBL27306478 | 0.82 | APP (0.30) | APP | |
| SCHEMBL27306484 | 0.81 | NR3C1 (0.31) | NR3C1 | |
| SCHEMBL27306611 | 0.80 | NR3C1 (0.32) | NR3C1 | |
| SCHEMBL27305823 | 0.78 | ALDH1A1 (0.41) | STK10SLKGSK3BBRAFNR3C1 | |
| SCHEMBL27306729 | 0.77 | MEN1 (0.32) | NR3C1MEN1KMT2A | |
| SCHEMBL27306821 | 0.76 | STK10 (0.36) | STK10SLKGSK3BBRAFPDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023235855-A1 | QUINOLINEAMINE ANTIDEGRADANT COMPOUNDS AND USES THEREOF | FLEXSYS AMERICA L.P. (US) | 2023-12-07 | — | — | WO | disclosed |