Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.43 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.39 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.39 |
| ▸ | HPGDS | O60760 | 1/20 | 0.39 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14904626 | 0.88 | HTT (0.41) | HTTCYP2A6ERCC5KDM4ETGFBR1 | |
| SCHEMBL14904711 | 0.86 | HTT (0.40) | HTTCYP2A6ERCC5TGFBR1RIPK2 | |
| SCHEMBL16562798 | 0.85 | RIPK2 (0.38) | HTTCYP2A6KDM4ETGFBR1RIPK2 | |
| SCHEMBL2689740 | 0.85 | CPB2 (0.41) | HTTCYP2A6ERCC5TGFBR1RIPK2 | |
| SCHEMBL2732597 | 0.84 | CYP2A6 (0.42) | CYP2A6ERCC5TGFBR1RIPK2HPGDS | |
| SCHEMBL4969169 | 0.84 | HTT (0.39) | HTTCYP2A6ERCC5TGFBR1RIPK2 | |
| SCHEMBL15356790 | 0.83 | QPCT (0.41) | HTTCYP2A6RIPK2NPC1RAB9A | |
| SCHEMBL15356762 | 0.83 | ALDH1A1 (0.38) | HTTCYP2A6ERCC5KDM4ETGFBR1 | |
| SCHEMBL15975575 | 0.82 | HTT (0.37) | HTTCYP2A6ERCC5KDM4ETGFBR1 | |
| SCHEMBL15356856 | 0.82 | QPCT (0.40) | HTTKDM4ERIPK2PRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2852284-A2 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | Dow AgroSciences LLC (US) | 2015-04-01 | — | — | EP | disclosed |
| EP-2840898-A2 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | Dow AgroSciences LLC (US) | 2015-03-04 | — | — | EP | disclosed |
| WO-2013162716-A9 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2014-11-06 | — | — | WO | disclosed |
| EP-2775843-A1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | Dow AgroSciences LLC (US) | 2014-09-17 | — | — | EP | disclosed |
| WO-2013162715-A2 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2013-10-31 | — | — | WO | disclosed |
| WO-2013162716-A2 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2013-10-31 | — | — | WO | disclosed |
| EP-2635278-A2 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | Dow AgroSciences LLC (US) | 2013-09-11 | — | — | EP | disclosed |
| WO-2013062981-A1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2013-05-02 | — | — | WO | disclosed |
| WO-2012061290-A2 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2012-05-10 | — | — | WO | disclosed |