SCHEMBL15975575

SCHEMBL15975575

CCN(C(=O)C(C)(C)CSC)c1cnn(-c2cccnc2)c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.37
RIPK1 Q13546 1/20 0.36
ALDH1A1 P00352 1/20 0.35
CYP2A6 P11509 1/20 0.35
DGAT1 O75907 1/20 0.35
TGFBR1 P36897 1/20 0.35
RIPK2 O43353 2/20 0.34
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33
PRMT5 O14744 1/20 0.33
ERCC5 P28715 1/20 0.33
ADORA2A P29274 1/20 0.33
ADORA2B P29275 1/20 0.33
ADORA1 P30542 1/20 0.33
MTOR P42345 2/20 0.32
ELANE P08246 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2B6 P20813 1/20 0.32
CYP2C19 P33261 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15975568 0.87 RIPK1 (0.37) RIPK1ALDH1A1CYP2A6TGFBR1RIPK2
SCHEMBL2730846 0.82 HTT (0.48) HTTALDH1A1CYP2A6TGFBR1RIPK2
SCHEMBL4968148 0.82 NPC1 (0.38) HTTRIPK1ALDH1A1CYP2A6DGAT1
SCHEMBL4969169 0.81 HTT (0.39) HTTALDH1A1CYP2A6DGAT1TGFBR1
SCHEMBL14904711 0.81 HTT (0.40) HTTRIPK1ALDH1A1CYP2A6DGAT1
SCHEMBL2689740 0.80 CPB2 (0.41) HTTRIPK1CYP2A6DGAT1TGFBR1
SCHEMBL15910376 0.78 PRMT5 (0.38) HTTALDH1A1CYP2A6DGAT1TGFBR1
SCHEMBL4970110 0.78 ALDH1A1 (0.37) HTTRIPK1ALDH1A1CYP2A6DGAT1
SCHEMBL14904626 0.78 HTT (0.41) HTTALDH1A1CYP2A6TGFBR1RIPK2
SCHEMBL15356764 0.76 IRAK4 (0.39) RIPK2NPC1RAB9APRMT5CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10165775-B2 Pesticidal compositions and processes related thereto DOW AGROSCIENCES LLC (US) 2019-01-01 US disclosed
US-9708288-B2 Pesticidal compositions and processes related thereto DOW AGROSCIENCES LLC (US) 2017-07-18 US disclosed
US-9708288-B2 Pesticidal compositions and processes related thereto DOW AGROSCIENCES LLC (US) 2017-07-18 US disclosed
US-9655365-B2 Pesticidal compositions and processes related thereto DOW AGROSCIENCES LLC (US) 2017-05-23 US disclosed
US-9655365-B2 Pesticidal compositions and processes related thereto DOW AGROSCIENCES LLC (US) 2017-05-23 US disclosed
US-9591857-B2 Pesticidal compositions and processes related thereto DOW AGROSCIENCES LLC (US) 2017-03-14 US disclosed
US-9591857-B2 Pesticidal compositions and processes related thereto DOW AGROSCIENCES LLC (US) 2017-03-14 US disclosed
US-9422278-B2 Pesticidal compositions and processes related thereto DOW AGROSCIENCES LLC (US) 2016-08-23 US disclosed
US-9422278-B2 Pesticidal compositions and processes related thereto DOW AGROSCIENCES LLC (US) 2016-08-23 US disclosed
US-9282739-B2 Pesticidal compositions and processes related thereto DOW AGROSCIENCES LLC (US) 2016-03-15 US disclosed
US-8937083-B2 Pesticidal compositions and processes related thereto DowAgroSciences, LLC (US) 2015-01-20 US disclosed
US-8937083-B2 Pesticidal compositions and processes related thereto DowAgroSciences, LLC (US) 2015-01-20 US disclosed
US-8901153-B2 Pesticidal compositions and processes related thereto DOW AGROSCIENCES, LLC. (US) 2014-12-02 US disclosed
US-8901153-B2 Pesticidal compositions and processes related thereto DOW AGROSCIENCES, LLC. (US) 2014-12-02 US disclosed
US-8815271-B2 Pesticidal compositions and processes related thereto DOW AGROSCIENCES, LLC. (US) 2014-08-26 US disclosed
US-8815271-B2 Pesticidal compositions and processes related thereto DOW AGROSCIENCES, LLC. (US) 2014-08-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10165775-B2 Pesticidal compositions and processes related thereto ACHE, DDT, PTMS HTT 4384/4885RIPK1 2832/4885ALDH1A1 1073/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.