Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 6/20 | 0.41 |
| ▸ | METAP2 | P50579 | 2/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.37 |
| ▸ | AXL | P30530 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TDO2 | P48775 | 2/20 | 0.31 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31206793 | 1.00 | NOS1 (0.41) | NOS1METAP2DYRK1ACSNK2A1AXL | |
| SCHEMBL22291031 | 0.79 | NOS1 (0.44) | NOS1METAP2DYRK1ACSNK2A1MAPT | |
| SCHEMBL30966926 | 0.79 | NOS1 (0.44) | NOS1METAP2DYRK1ACSNK2A1MAPT | |
| SCHEMBL17099469 | 0.76 | NOS1 (0.41) | NOS1METAP2DYRK1ACSNK2A1AXL | |
| SCHEMBL3601695 | 0.72 | NOS1 (0.50) | NOS1METAP2DYRK1ACSNK2A1AXL | |
| SCHEMBL2430496 | 0.72 | NOS1 (0.50) | NOS1METAP2DYRK1ACSNK2A1AXL | |
| SCHEMBL25204558 | 0.72 | AXL (0.44) | NOS1METAP2DYRK1ACSNK2A1AXL | |
| SCHEMBL35211500 | 0.72 | METAP2 (0.39) | NOS1METAP2DYRK1ATRPA1 | |
| SCHEMBL35210765 | 0.69 | NOS1 (0.36) | NOS1METAP2DYRK1ACSNK2A1AXL | |
| SCHEMBL21631684 | 0.68 | NOS1 (0.42) | NOS1METAP2DYRK1ACSNK2A1AXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4705308-A1 | EGFR INHIBITORS FOR TREATING DISEASE | Blossomhill Therapeutics, Inc. (US) | 2026-03-11 | — | — | EP | disclosed |
| WO-2024229087-A1 | EGFR INHIBITORS FOR TREATING DISEASE | BLOSSOMHILL THERAPEUTICS, INC. (US) | 2024-11-07 | — | — | WO | disclosed |
| WO-2024229091-A1 | EGFR INHIBITORS FOR TREATING DISEASE | BLOSSOMHILL THERAPEUTICS, INC. (US) | 2024-11-07 | — | — | WO | disclosed |
| WO-2024025896-A2 | PROTEIN KINASE C (PKC) THETA INHIBITOR COMPOUNDS | EVOMMUNE, INC. (US) | 2024-02-01 | — | — | WO | disclosed |