Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 9/20 | 0.44 |
| ▸ | KDR | P35968 | 6/20 | 0.41 |
| ▸ | BRAF | P15056 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | ESRRA | P11474 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30885063 | 1.00 | MALT1 (0.44) | MALT1KDRBRAFKDM4EMAPT | |
| SCHEMBL27096932 | 0.89 | MALT1 (0.45) | MALT1KDRBRAFKDM4EMAPT | |
| SCHEMBL30729915 | 0.87 | NPC1 (0.46) | MALT1KDRBRAFKDM4EMAPT | |
| SCHEMBL27096974 | 0.79 | MAP4K4 (0.41) | MALT1KDM4EMAPTALDH1A1 | |
| SCHEMBL30729909 | 0.79 | MAP4K4 (0.41) | MALT1KDM4EMAPTALDH1A1 | |
| SCHEMBL30729912 | 0.78 | ALDH1A1 (0.49) | KDRBRAFMAPTRORCESRRA | |
| SCHEMBL27305474 | 0.78 | ALDH1A1 (0.49) | KDRBRAFMAPTRORCESRRA | |
| SCHEMBL30885060 | 0.75 | KDR (0.57) | KDRBRAF | |
| SCHEMBL27305478 | 0.75 | KDR (0.57) | KDRBRAF | |
| SCHEMBL29834832 | 0.72 | MAP4K4 (0.39) | KDRBRAFKDM4EMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024026056-A2 | HETEROARYL COMPOUNDS AS EGFR INHIBITORS AND THEIR USES | ACCUTAR BIOTECHNOLOGY, INC. (US) | 2024-02-01 | — | — | WO | disclosed |